TY - GEN
T1 - NUMERICAL MODELING OF MICROFLUIDIC GENERATION AND SHOOTING OF PICOLITER LIQUID DROPLETS USING AIR FLOW
AU - Chen, Po Yin
AU - Chen, Chihchen
AU - Kazoe, Yutaka
AU - Morikawa, Kyojiro
AU - Kitamori, Takehiko
N1 - Publisher Copyright:
© 2022 MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.
PY - 2022
Y1 - 2022
N2 - Droplet microfluidics has found diverse applications in the manipulation, detection and synthesis of biological and chemical objects. Generating droplets by using air sheath flow is especially advantageous to further reduce contamination and facilitate evaporation. We have developed a microfluidic droplet shooter capable of injecting samples to the mass spectrometer (MS) at ~100% efficiency. The generation of droplets is due to the air drag force and instability of the gas-liquid interface. Herein, numerical simulation is established to delineate the complex flow fields and fluid-surface interactions inside the shooter. The numerical and experimental results agree well, providing insights for developing droplet microfluidics.
AB - Droplet microfluidics has found diverse applications in the manipulation, detection and synthesis of biological and chemical objects. Generating droplets by using air sheath flow is especially advantageous to further reduce contamination and facilitate evaporation. We have developed a microfluidic droplet shooter capable of injecting samples to the mass spectrometer (MS) at ~100% efficiency. The generation of droplets is due to the air drag force and instability of the gas-liquid interface. Herein, numerical simulation is established to delineate the complex flow fields and fluid-surface interactions inside the shooter. The numerical and experimental results agree well, providing insights for developing droplet microfluidics.
KW - Air Floating Droplet Generation
KW - Droplet Microfluidics
KW - Gas-Liquid Two-Phase Flow
KW - Numerical Simulation
UR - https://www.scopus.com/pages/publications/85175706437
UR - https://www.scopus.com/pages/publications/85175706437#tab=citedBy
M3 - Conference contribution
AN - SCOPUS:85175706437
T3 - MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 809
EP - 810
BT - MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022
Y2 - 23 October 2022 through 27 October 2022
ER -