Occurrence of infection following prostate biopsy procedures in Japan Japanese Research Group for Urinary Tract Infection (JRGU)-A multi-center retrospective study

Yoshikazu Togo; Tatsuhiko Kubo; Rikiya Taoka; Yoshiki Hiyama; Teruhisa Uehara; Jiroh Hashimoto; Yuichiro Kurimura; Satoshi Takahashi; Taiji Tsukamoto; Jun Miyazaki; Hiroyuki Nishiyama; Shinichiro Kira; Hiroshi Kiyota; Satoshi Yazawa; Naoya Niwa; Hiroshi Hongo; Mototsugu Oya; Taku Kato; Mitsuru Yasuda; Takashi Deguchi; Kiyohito Ishikawa; Kiyotaka Hoshinaga; Minori Matsumoto; Katsumi Shigemura; Kazushi Tanaka; Soichi Arakawa; Masato Fujisawa; Koichiro Wada; Shinya Uehara; Toyohiko Watanabe; Hiromi Kumon; Kanao Kobayashi; Akio Matsubara; Masahiro Matsumoto; Takehiko Sho; Ryoichi Hamasuna; Tetsuro Matsumoto; Hiroshi Hayami; Masayuki Nakagawa; Shingo Yamamoto

doi:10.1016/j.jiac.2013.10.003

Occurrence of infection following prostate biopsy procedures in Japan Japanese Research Group for Urinary Tract Infection (JRGU)-A multi-center retrospective study

Yoshikazu Togo, Tatsuhiko Kubo, Rikiya Taoka, Yoshiki Hiyama, Teruhisa Uehara, Jiroh Hashimoto, Yuichiro Kurimura, Satoshi Takahashi, Taiji Tsukamoto, Jun Miyazaki, Hiroyuki Nishiyama, Shinichiro Kira, Hiroshi Kiyota, Satoshi Yazawa, Naoya Niwa, Hiroshi Hongo, Mototsugu Oya, Taku Kato, Mitsuru Yasuda, Takashi DeguchiKiyohito Ishikawa, Kiyotaka Hoshinaga, Minori Matsumoto, Katsumi Shigemura, Kazushi Tanaka, Soichi Arakawa, Masato Fujisawa, Koichiro Wada, Shinya Uehara, Toyohiko Watanabe, Hiromi Kumon, Kanao Kobayashi, Akio Matsubara, Masahiro Matsumoto, Takehiko Sho, Ryoichi Hamasuna, Tetsuro Matsumoto, Hiroshi Hayami, Masayuki Nakagawa, Shingo Yamamoto

Department of Urology

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

We retrospectively investigated the incidence of genitourinary tract infection in 5895 patients who underwent transrectal and/or transperineal prostate biopsy procedure between January and December 2011 at 46 institutions belonging to Japanese Research Group for Urinary Tract Infection (JRGU). The total rate of genitourinary tract infection after prostate biopsy was 0.76%, while that following transrectal procedure was 0.83% and following transperineal procedure was 0.57%, which were not significantly different. In contrast, febrile infection associated with a fever (≥38 °C) occurred significantly more frequently after transrectal (0.71%) than transperineal (0.16%) approach (P = 0.04). Notably, in infectious cases, Escherichia coli was most frequently isolated. Of the 9 E. coli strains isolated by urine culture, 6 (66.7%) produced extended spectrum β-lactamase (ESBL) and 7 (77.8%) showed levofloxacin resistance. Similarly, of 6 E. coli strains isolated by blood culture, 4 (66.7%) produced ESBL and 6 (100%) showed levofloxacin resistance. When the efficacy of antimicrobial prophylaxis (AMP) with levofloxacin for the patients undergoing transrectal or transperineal biopsy was compared between a single dose (500 mg) and that given for 2 or more days, no significant difference was observed for the rate of infection (transrectal: 0.82% vs. 1.04%, p = 0.94; transperineal: 0.30% vs. 0.46%, p = 0.68).

Original language	English
Pages (from-to)	232-237
Number of pages	6
Journal	Journal of Infection and Chemotherapy
Volume	20
Issue number	4
DOIs	https://doi.org/10.1016/j.jiac.2013.10.003
Publication status	Published - 2014 Apr

Keywords

Antimicrobial prophylaxis
Genitourinary tract infection
Prostate biopsy
Prostate cancer

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases
Pharmacology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jiac.2013.10.003

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Togo, Y., Kubo, T., Taoka, R., Hiyama, Y., Uehara, T., Hashimoto, J., Kurimura, Y., Takahashi, S., Tsukamoto, T., Miyazaki, J., Nishiyama, H., Kira, S., Kiyota, H., Yazawa, S., Niwa, N., Hongo, H., Oya, M., Kato, T., Yasuda, M., ... Yamamoto, S. (2014). Occurrence of infection following prostate biopsy procedures in Japan Japanese Research Group for Urinary Tract Infection (JRGU)-A multi-center retrospective study. Journal of Infection and Chemotherapy, 20(4), 232-237. https://doi.org/10.1016/j.jiac.2013.10.003

Togo, Y, Kubo, T, Taoka, R, Hiyama, Y, Uehara, T, Hashimoto, J, Kurimura, Y, Takahashi, S, Tsukamoto, T, Miyazaki, J, Nishiyama, H, Kira, S, Kiyota, H, Yazawa, S, Niwa, N, Hongo, H, Oya, M, Kato, T, Yasuda, M, Deguchi, T, Ishikawa, K, Hoshinaga, K, Matsumoto, M, Shigemura, K, Tanaka, K, Arakawa, S, Fujisawa, M, Wada, K, Uehara, S, Watanabe, T, Kumon, H, Kobayashi, K, Matsubara, A, Matsumoto, M, Sho, T, Hamasuna, R, Matsumoto, T, Hayami, H, Nakagawa, M & Yamamoto, S 2014, 'Occurrence of infection following prostate biopsy procedures in Japan Japanese Research Group for Urinary Tract Infection (JRGU)-A multi-center retrospective study', Journal of Infection and Chemotherapy, vol. 20, no. 4, pp. 232-237. https://doi.org/10.1016/j.jiac.2013.10.003

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title = "Occurrence of infection following prostate biopsy procedures in Japan Japanese Research Group for Urinary Tract Infection (JRGU)-A multi-center retrospective study",

abstract = "We retrospectively investigated the incidence of genitourinary tract infection in 5895 patients who underwent transrectal and/or transperineal prostate biopsy procedure between January and December 2011 at 46 institutions belonging to Japanese Research Group for Urinary Tract Infection (JRGU). The total rate of genitourinary tract infection after prostate biopsy was 0.76%, while that following transrectal procedure was 0.83% and following transperineal procedure was 0.57%, which were not significantly different. In contrast, febrile infection associated with a fever (≥38 °C) occurred significantly more frequently after transrectal (0.71%) than transperineal (0.16%) approach (P = 0.04). Notably, in infectious cases, Escherichia coli was most frequently isolated. Of the 9 E. coli strains isolated by urine culture, 6 (66.7%) produced extended spectrum β-lactamase (ESBL) and 7 (77.8%) showed levofloxacin resistance. Similarly, of 6 E. coli strains isolated by blood culture, 4 (66.7%) produced ESBL and 6 (100%) showed levofloxacin resistance. When the efficacy of antimicrobial prophylaxis (AMP) with levofloxacin for the patients undergoing transrectal or transperineal biopsy was compared between a single dose (500 mg) and that given for 2 or more days, no significant difference was observed for the rate of infection (transrectal: 0.82% vs. 1.04%, p = 0.94; transperineal: 0.30% vs. 0.46%, p = 0.68).",

keywords = "Antimicrobial prophylaxis, Genitourinary tract infection, Prostate biopsy, Prostate cancer",

author = "Yoshikazu Togo and Tatsuhiko Kubo and Rikiya Taoka and Yoshiki Hiyama and Teruhisa Uehara and Jiroh Hashimoto and Yuichiro Kurimura and Satoshi Takahashi and Taiji Tsukamoto and Jun Miyazaki and Hiroyuki Nishiyama and Shinichiro Kira and Hiroshi Kiyota and Satoshi Yazawa and Naoya Niwa and Hiroshi Hongo and Mototsugu Oya and Taku Kato and Mitsuru Yasuda and Takashi Deguchi and Kiyohito Ishikawa and Kiyotaka Hoshinaga and Minori Matsumoto and Katsumi Shigemura and Kazushi Tanaka and Soichi Arakawa and Masato Fujisawa and Koichiro Wada and Shinya Uehara and Toyohiko Watanabe and Hiromi Kumon and Kanao Kobayashi and Akio Matsubara and Masahiro Matsumoto and Takehiko Sho and Ryoichi Hamasuna and Tetsuro Matsumoto and Hiroshi Hayami and Masayuki Nakagawa and Shingo Yamamoto",

year = "2014",

month = apr,

doi = "10.1016/j.jiac.2013.10.003",

language = "English",

volume = "20",

pages = "232--237",

journal = "Journal of Infection and Chemotherapy",

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T1 - Occurrence of infection following prostate biopsy procedures in Japan Japanese Research Group for Urinary Tract Infection (JRGU)-A multi-center retrospective study

AU - Togo, Yoshikazu

AU - Kubo, Tatsuhiko

AU - Taoka, Rikiya

AU - Hiyama, Yoshiki

AU - Uehara, Teruhisa

AU - Hashimoto, Jiroh

AU - Kurimura, Yuichiro

AU - Takahashi, Satoshi

AU - Tsukamoto, Taiji

AU - Miyazaki, Jun

AU - Nishiyama, Hiroyuki

AU - Kira, Shinichiro

AU - Kiyota, Hiroshi

AU - Yazawa, Satoshi

AU - Niwa, Naoya

AU - Hongo, Hiroshi

AU - Oya, Mototsugu

AU - Kato, Taku

AU - Yasuda, Mitsuru

AU - Deguchi, Takashi

AU - Ishikawa, Kiyohito

AU - Hoshinaga, Kiyotaka

AU - Matsumoto, Minori

AU - Shigemura, Katsumi

AU - Tanaka, Kazushi

AU - Arakawa, Soichi

AU - Fujisawa, Masato

AU - Wada, Koichiro

AU - Uehara, Shinya

AU - Watanabe, Toyohiko

AU - Kumon, Hiromi

AU - Kobayashi, Kanao

AU - Matsubara, Akio

AU - Matsumoto, Masahiro

AU - Sho, Takehiko

AU - Hamasuna, Ryoichi

AU - Matsumoto, Tetsuro

AU - Hayami, Hiroshi

AU - Nakagawa, Masayuki

AU - Yamamoto, Shingo

PY - 2014/4

Y1 - 2014/4

N2 - We retrospectively investigated the incidence of genitourinary tract infection in 5895 patients who underwent transrectal and/or transperineal prostate biopsy procedure between January and December 2011 at 46 institutions belonging to Japanese Research Group for Urinary Tract Infection (JRGU). The total rate of genitourinary tract infection after prostate biopsy was 0.76%, while that following transrectal procedure was 0.83% and following transperineal procedure was 0.57%, which were not significantly different. In contrast, febrile infection associated with a fever (≥38 °C) occurred significantly more frequently after transrectal (0.71%) than transperineal (0.16%) approach (P = 0.04). Notably, in infectious cases, Escherichia coli was most frequently isolated. Of the 9 E. coli strains isolated by urine culture, 6 (66.7%) produced extended spectrum β-lactamase (ESBL) and 7 (77.8%) showed levofloxacin resistance. Similarly, of 6 E. coli strains isolated by blood culture, 4 (66.7%) produced ESBL and 6 (100%) showed levofloxacin resistance. When the efficacy of antimicrobial prophylaxis (AMP) with levofloxacin for the patients undergoing transrectal or transperineal biopsy was compared between a single dose (500 mg) and that given for 2 or more days, no significant difference was observed for the rate of infection (transrectal: 0.82% vs. 1.04%, p = 0.94; transperineal: 0.30% vs. 0.46%, p = 0.68).

AB - We retrospectively investigated the incidence of genitourinary tract infection in 5895 patients who underwent transrectal and/or transperineal prostate biopsy procedure between January and December 2011 at 46 institutions belonging to Japanese Research Group for Urinary Tract Infection (JRGU). The total rate of genitourinary tract infection after prostate biopsy was 0.76%, while that following transrectal procedure was 0.83% and following transperineal procedure was 0.57%, which were not significantly different. In contrast, febrile infection associated with a fever (≥38 °C) occurred significantly more frequently after transrectal (0.71%) than transperineal (0.16%) approach (P = 0.04). Notably, in infectious cases, Escherichia coli was most frequently isolated. Of the 9 E. coli strains isolated by urine culture, 6 (66.7%) produced extended spectrum β-lactamase (ESBL) and 7 (77.8%) showed levofloxacin resistance. Similarly, of 6 E. coli strains isolated by blood culture, 4 (66.7%) produced ESBL and 6 (100%) showed levofloxacin resistance. When the efficacy of antimicrobial prophylaxis (AMP) with levofloxacin for the patients undergoing transrectal or transperineal biopsy was compared between a single dose (500 mg) and that given for 2 or more days, no significant difference was observed for the rate of infection (transrectal: 0.82% vs. 1.04%, p = 0.94; transperineal: 0.30% vs. 0.46%, p = 0.68).

KW - Antimicrobial prophylaxis

KW - Genitourinary tract infection

KW - Prostate biopsy

KW - Prostate cancer

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ER -

Occurrence of infection following prostate biopsy procedures in Japan Japanese Research Group for Urinary Tract Infection (JRGU)-A multi-center retrospective study

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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