Ocular fatigue is the major symptom of dry eye

Ikuko Toda, Hiroshi Fujishima, Kazuo Tsubota

Research output: Contribution to journalArticlepeer-review

209 Citations (Scopus)


ABSTRACT A total of 524 consecutive new patients (195 male, 329 female, 434±208 yo) were evaluated for the presence of ocular fatigue and/or dry eye Dry eye was diagnosed based on our criteria, which included symptoms, vital staining, break‐up time (BUT) measurement, and the Schirmer test Among all the patients, 212% (111/524) reported symptoms of ocular fatigue and 153% (80/524) were diagnosed as having dry eye with symptoms Of the 111 patients who complained of ocular fatigue, 514% (57/111) had dry eye, which was significantly higher than the 153% for the entire group (p<0001) Additionally, 713% (57/80) of dry eye patients with symptoms complained of ocular fatigue, which was also significantly higher than the 212% among all patients (p<0001) Dry eye patients had a greater number of complaints (43±21 per patient) compared to controls (19±13 per patient) (p<0001) These findings suggest that there is a strong relation between ocular fatigue and dry eye 1993 Institution Acta Ophthalmologica Scandinavica

Original languageEnglish
Pages (from-to)347-352
Number of pages6
JournalActa ophthalmologica
Issue number3
Publication statusPublished - 1993 Jun
Externally publishedYes


  • Schirmer test
  • double vital staining
  • dry eye
  • ocular fatigue

ASJC Scopus subject areas

  • Ophthalmology


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