Oxidative deprotection of 1,3-dithiane group using NaClO2 and NaH2PO4 in aqueous methanol

Takahiro Ichige; Annu Miyake; Naoki Kanoh; Masaya Nakata

doi:10.1055/s-2004-829558

Oxidative deprotection of 1,3-dithiane group using NaClO₂ and NaH₂PO₄ in aqueous methanol

Takahiro Ichige, Annu Miyake, Naoki Kanoh, Masaya Nakata

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

The 1,3-dithiane group was oxidatively deprotected under the conditions of sodium chlorite, sodium dihydrogenphosphate, and 2-methyl-2-butene in 3:1 methanol-water at room temperature in good yield.

Original language	English
Pages (from-to)	1686-1690
Number of pages	5
Journal	Synlett
Issue number	10
DOIs	https://doi.org/10.1055/s-2004-829558
Publication status	Published - 2004 Aug 9
Externally published	Yes

Keywords

Deprotection
Protecting groups
Sodium chlorite
Sodium dihydrogenphosphate
Thioacetals

ASJC Scopus subject areas

Organic Chemistry

Access to Document

10.1055/s-2004-829558

Cite this

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title = "Oxidative deprotection of 1,3-dithiane group using NaClO2 and NaH2PO4 in aqueous methanol",

abstract = "The 1,3-dithiane group was oxidatively deprotected under the conditions of sodium chlorite, sodium dihydrogenphosphate, and 2-methyl-2-butene in 3:1 methanol-water at room temperature in good yield.",

keywords = "Deprotection, Protecting groups, Sodium chlorite, Sodium dihydrogenphosphate, Thioacetals",

author = "Takahiro Ichige and Annu Miyake and Naoki Kanoh and Masaya Nakata",

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T1 - Oxidative deprotection of 1,3-dithiane group using NaClO2 and NaH2PO4 in aqueous methanol

AU - Ichige, Takahiro

AU - Miyake, Annu

AU - Kanoh, Naoki

AU - Nakata, Masaya

PY - 2004/8/9

Y1 - 2004/8/9

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AB - The 1,3-dithiane group was oxidatively deprotected under the conditions of sodium chlorite, sodium dihydrogenphosphate, and 2-methyl-2-butene in 3:1 methanol-water at room temperature in good yield.

KW - Deprotection

KW - Protecting groups

KW - Sodium chlorite

KW - Sodium dihydrogenphosphate

KW - Thioacetals

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