Pancreatic metastasis from renal cell carcinoma extending into the main pancreatic duct: A case report

Shinichi Yachida, Noriyoshi Fukushima, Yae Kanai, Satoshi Nimura, Kazuaki Shimada, Junji Yamamoto, Michiie Sakamoto

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36 Citations (Scopus)


While metastasis to the pancreas is uncommon, it may occur from renal cell carcinomas (RCCs). We here present a case of pancreatic metastasis from RCC extending into the main pancreatic duct (MPD) in a 66-year-old Japanese man. The patient had a history of RCC treated with a radical nephrectomy 17 years previously and was found to have a mass ∼2 cm in diameter in the body of the pancreas on radiological images. The patient was suspected of having pancreatic metastasis from RCC and underwent a distal pancreatectomy with splenectomy. Histologically, the tumor consisted of cells arranged in trabecular and alveolar structures with clear or eosinophilic granular cytoplasm, compatible with a metastatic RCC. The pancreatic tumor extended into the MPD with the stream of pancreatic juice. This condition is similar to RCC extension into the renal vein and the inferior vena cava. In conclusion, although extension into the MPD may be rare, such a growth pattern may be characteristic of metastases from RCCs.

Original languageEnglish
Pages (from-to)315-317
Number of pages3
JournalJapanese journal of clinical oncology
Issue number8
Publication statusPublished - 2002 Aug 1
Externally publishedYes


  • Main pancreatic duct
  • Pancreatic metastasis
  • Renal cell carcinoma

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research


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