TY - JOUR
T1 - Paraneoplastic cerebellar degeneration with fallopian tube adenocarcinoma
AU - Tanaka, Yudai
AU - Suzuki, Nao
AU - Takao, Masaki
AU - Ichikawa, Akiko
AU - Susumu, Nobuyuki
AU - Aoki, Daisuke
PY - 2005/11
Y1 - 2005/11
N2 - Background. Paraneoplastic cerebellar degeneration (PCD) is rarely caused by fallopian tube adenocarcinoma. Case. We present a patient with PCD and fallopian tube cancer. Anti-Yo antibody, one of an anti-neuronal antibody, was positive in serum and cerebrospinal fluid. She was also positive for HLA A24, which is common in patients with PCD. Radical surgery did not significantly ameliorate her neurological impairment, although the dysarthria improved slightly. Conclusion. This case highlights the importance of detecting the underlying malignancy in patients with subacute neurological impairment and shows that fallopian tube cancer can potentially cause PCD.
AB - Background. Paraneoplastic cerebellar degeneration (PCD) is rarely caused by fallopian tube adenocarcinoma. Case. We present a patient with PCD and fallopian tube cancer. Anti-Yo antibody, one of an anti-neuronal antibody, was positive in serum and cerebrospinal fluid. She was also positive for HLA A24, which is common in patients with PCD. Radical surgery did not significantly ameliorate her neurological impairment, although the dysarthria improved slightly. Conclusion. This case highlights the importance of detecting the underlying malignancy in patients with subacute neurological impairment and shows that fallopian tube cancer can potentially cause PCD.
KW - Anti-Yo antibody
KW - Fallopian tube carcinoma
KW - Paraneoplastic cerebellar degeneration
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U2 - 10.1016/j.ygyno.2005.06.064
DO - 10.1016/j.ygyno.2005.06.064
M3 - Article
C2 - 16126258
AN - SCOPUS:27144555375
SN - 0090-8258
VL - 99
SP - 500
EP - 503
JO - Gynecologic Oncology
JF - Gynecologic Oncology
IS - 2
ER -
