Pathogenesis of AAA Rupture

Naoki Fujimura; Ronald L. Dalman

doi:10.1007/978-3-319-23844-9_4

Pathogenesis of AAA Rupture

Naoki Fujimura
, Ronald L. Dalman

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Mechanisms of abdominal aortic aneurysm degeneration have been the subject of intense investigation over the last 20 years. As noted in Fig. 4.1, the pathogenesis of abdominal aortic aneurysm disease involves a symphony of interactions between genetic risk, environmental exposures, and interplay between aortic mural inflammation, angiogenesis, smooth muscle cell and elastin depletion, wall strain, and dysfunctional and insufficient regenerative responses of the extracellular matrix [1–10] (Table 4. 1).

Original language	English
Title of host publication	Ruptured Abdominal Aortic Aneurysm
Subtitle of host publication	the Definitive Manual
Publisher	Springer International Publishing
Pages	49-65
Number of pages	17
ISBN (Electronic)	9783319238449
ISBN (Print)	9783319238432
DOIs	https://doi.org/10.1007/978-3-319-23844-9_4
Publication status	Published - 2017 Jan 1
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1007/978-3-319-23844-9_4

Cite this

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title = "Pathogenesis of AAA Rupture",

abstract = "Mechanisms of abdominal aortic aneurysm degeneration have been the subject of intense investigation over the last 20 years. As noted in Fig. 4.1, the pathogenesis of abdominal aortic aneurysm disease involves a symphony of interactions between genetic risk, environmental exposures, and interplay between aortic mural inflammation, angiogenesis, smooth muscle cell and elastin depletion, wall strain, and dysfunctional and insufficient regenerative responses of the extracellular matrix [1{\textendash}10] (Table 4. 1).",

author = "Naoki Fujimura and Dalman, \{Ronald L.\}",

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N2 - Mechanisms of abdominal aortic aneurysm degeneration have been the subject of intense investigation over the last 20 years. As noted in Fig. 4.1, the pathogenesis of abdominal aortic aneurysm disease involves a symphony of interactions between genetic risk, environmental exposures, and interplay between aortic mural inflammation, angiogenesis, smooth muscle cell and elastin depletion, wall strain, and dysfunctional and insufficient regenerative responses of the extracellular matrix [1–10] (Table 4. 1).

AB - Mechanisms of abdominal aortic aneurysm degeneration have been the subject of intense investigation over the last 20 years. As noted in Fig. 4.1, the pathogenesis of abdominal aortic aneurysm disease involves a symphony of interactions between genetic risk, environmental exposures, and interplay between aortic mural inflammation, angiogenesis, smooth muscle cell and elastin depletion, wall strain, and dysfunctional and insufficient regenerative responses of the extracellular matrix [1–10] (Table 4. 1).

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Pathogenesis of AAA Rupture

Abstract

ASJC Scopus subject areas

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