TY - JOUR
T1 - Peptidoglycan as Nod1 ligand; Fragment structures in the environment, chemical synthesis, and their innate immunostimulation
AU - Fujimoto, Yukari
AU - Pradipta, Ambara Rachmat
AU - Inohara, Naohiro
AU - Fukase, Koichi
PY - 2012/5
Y1 - 2012/5
N2 - This review focuses on the recent revealing of the immunostimulatory bacterial cell wall peptidoglycan (PGN) fragments as Nod1 ligands, especially a newly developed chemical synthesis of the partial structures, fragment structures in the environment and bacterial supernatant, and the immunostimulatory activities of the Nod1 ligands.
AB - This review focuses on the recent revealing of the immunostimulatory bacterial cell wall peptidoglycan (PGN) fragments as Nod1 ligands, especially a newly developed chemical synthesis of the partial structures, fragment structures in the environment and bacterial supernatant, and the immunostimulatory activities of the Nod1 ligands.
UR - http://www.scopus.com/inward/record.url?scp=84859560525&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84859560525&partnerID=8YFLogxK
U2 - 10.1039/c2np00091a
DO - 10.1039/c2np00091a
M3 - Review article
C2 - 22370813
AN - SCOPUS:84859560525
SN - 0265-0568
VL - 29
SP - 568
EP - 579
JO - Natural Product Reports
JF - Natural Product Reports
IS - 5
ER -