Perinatal immunization education improves immunization rates and knowledge: A randomized controlled trial

Aya Saitoh, Satoko Nagata, Akihiko Saitoh, Yuki Tsukahara, Florin Vaida, Tomoyoshi Sonobe, Hajime Kamiya, Takashi Naruse, Sachiyo Murashima

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)


Objectives: To determine if providing perinatal immunization education positively changes the immunization status of infants, influences the infant immunization knowledge, attitudes and beliefs of mothers and affects the intent to vaccinate children in Japan where immunization education is limited. Methods: Pregnant women were recruited from three sites in Tokyo, Japan and were assigned to two intervention (pre- or postnatal education) groups and a control group. The immunization status of infants was assessed and a written survey was performed before and after the intervention. Results: Among 119 study participants, 106 subjects replied to the post-survey. The intervention groups (34.3%) had higher immunization rates in infants at three months of age than the control group (8.3%) (P = 0.005); however, no differences were observed between the prenatal (29.4%) and postnatal groups (38.9%) (P = 0.40). The percentage of women intended to vaccinate their infants was higher in the intervention groups (61.4%) compared to the control group (33.3%) (P = 0.01). The improvement in score for basic knowledge was higher in the intervention groups, particularly in the prenatal group (mean ± S.D.: 3.4 ± 1.8) compared to the control (1.9 ± 1.9) (P = 0.003). Conclusions: Perinatal immunization education improved the immunization status of infants, increased the women's knowledge on immunization and intention to vaccinate their infants.

Original languageEnglish
Pages (from-to)398-405
Number of pages8
JournalPreventive Medicine
Issue number6
Publication statusPublished - 2013 Jun


  • Education
  • Infantile immunization
  • Parents
  • Perinatal
  • Vaccination rate

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health


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