Personality assessment based on the five-factor model of personality structure in patients with primary open-angle glaucoma

Fumihiko Mabuchi, Kimio Yoshimura, Kenji Kashiwagi, Kunihiko Shioe, Shigenobu Kanba, Hiroyuki Iijima, Shigeo Tsukahara

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


Purpose: Several characteristic personality types have been reported for glaucoma patients in previous studies. However, none of the previous studies used a common structural theory of personality. In this study, we conducted a multicenter cross-sectional case-control study using the recently established five-factor model of personality structure. Methods: Personality was evaluated using the Neuroticism Extraversion Openness Five-Factor Inventory (NEO-FFI), which is a questionnaire specifically designed to test the five-factor model of personality: neuroticism (N), extraversion (E), openness (O), agreeableness (A), and conscientiousness (C). Eligible questionnaires were obtained from 196 patients with primary open-angle glaucoma (POAG) (99 men, 97 women) and 223 reference subjects with no ocular disease except cataract (87 men, 136 women). The mean score of each NEO-FFI factor for POAG patients was compared to the scores for the reference subjects. Results: Compared with the reference subjects, the mean N score was significantly higher (P = 0.013), the mean scores for A and C were significantly lower (P = 0.007 and P = 0.001, respectively), and the mean E score tended to be lower (P = 0.055) in male POAG patients. The mean E score was significantly lower (P = 0.023) in female POAG patients. Conclusions: Characteristic personality traits were noted in POAG patients, and a more significant relationship was found between personality and glaucoma in men than in women.

Original languageEnglish
Pages (from-to)31-35
Number of pages5
JournalJapanese Journal of Ophthalmology
Issue number1
Publication statusPublished - 2005 Jan
Externally publishedYes


  • Five-factor model of personality structure
  • Personality
  • Primary open-angle glaucoma patients

ASJC Scopus subject areas

  • Ophthalmology


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