Platinum(II)-catalyzed generation and [3+2] cycloaddition reaction of α,β-unsaturated carbene complex intermediates for the preparation of polycyclic compounds

Kodai Saito; Hideyuki Sogou; Takuya Suga; Hiroyuki Kusama; Nobuharu Iwasawa

doi:10.1021/ja108586d

Platinum(II)-catalyzed generation and [3+2] cycloaddition reaction of α,β-unsaturated carbene complex intermediates for the preparation of polycyclic compounds

Kodai Saito, Hideyuki Sogou, Takuya Suga, Hiroyuki Kusama, Nobuharu Iwasawa

Research output: Contribution to journal › Article › peer-review

90 Citations (Scopus)

Abstract

Pt(II)-catalyzed generation of unsaturated carbene complex intermediates from various propargyl ether derivatives based on electrophilic activation of alkynes was realized. These in situ generated unsaturated carbene complexes undergo [3+2] cycloaddition reaction with various vinyl ethers, leading to efficient formation of indoles, naphthols, and benzofuran fused with a five-membered ring in high yields.

Original language	English
Pages (from-to)	689-691
Number of pages	3
Journal	Journal of the American Chemical Society
Volume	133
Issue number	4
DOIs	https://doi.org/10.1021/ja108586d
Publication status	Published - 2011 Feb 2
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja108586d

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Platinum(II)-catalyzed generation and [3+2] cycloaddition reaction of α,β-unsaturated carbene complex intermediates for the preparation of polycyclic compounds. / Saito, Kodai; Sogou, Hideyuki; Suga, Takuya et al.
In: Journal of the American Chemical Society, Vol. 133, No. 4, 02.02.2011, p. 689-691.

Research output: Contribution to journal › Article › peer-review

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AU - Kusama, Hiroyuki

AU - Iwasawa, Nobuharu

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Platinum(II)-catalyzed generation and [3+2] cycloaddition reaction of α,β-unsaturated carbene complex intermediates for the preparation of polycyclic compounds

Abstract

ASJC Scopus subject areas

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