Porous apatite carrier prepared by hydrothermal method

Giichiro Kawachi, Shuji Sasaki, Kazuhiko Nakahara, Emile Hideki Ishida, Koji Ioku

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


Porous apatite carrier with high selectivity of adsorption was prepared by using hydrothermal method. α-TCP as the starting material was changed into hydroxyapatite at the temperature above 120°C for the period over 3 h under saturated vapor pressure. Porous apatite carriers were composed of rod-shaped crystals with non-stoichiometric hydroxyapatite composition. Since HA crystals had rod like shape, the area of a-surface was larger than that of c-surface. This carrier had higher selectivity for bovine serum albumin (acidic protein) than lysozyme chloride (basic protein). This material must be suitable as scaffold for cultured bone, for bone graft material and for drug delivery system (DDS).

Original languageEnglish
Pages (from-to)935-938
Number of pages4
JournalKey Engineering Materials
Volume309-311 II
Publication statusPublished - 2006
Externally publishedYes


  • Apatite
  • Ca deficit hydroxyapatite
  • Hydrothermal treatment
  • Scaffold

ASJC Scopus subject areas

  • General Materials Science
  • Mechanics of Materials
  • Mechanical Engineering


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