TY - JOUR
T1 - Prefrontal activation associated with social attachment
T2 - Facial-emotion recognition in mothers and infants
AU - Minagawa-Kawai, Yasuyo
AU - Matsuoka, Sunao
AU - Dan, Ippeita
AU - Naoi, Nozomi
AU - Nakamura, Katsuki
AU - Kojima, Shozo
N1 - Funding Information:
Japan Agency of Science and Technology; the Global Center of Excellence program Keio University; and Program for Promotion of Basic Research Activities for Innovative Bioscience (PROBRAIN).
PY - 2009/2
Y1 - 2009/2
N2 - Attachment between mothers and infants is the most primitive and primary form of human social relationship. Many reports have suggested that the orbitofrontal cortex (OFC) plays a significant role in this attachment; however, only a select few provide experimental neurophysiological evidence. In the present study, to determine the neural substrates underlying the social and emotional attachment between mothers and infants, we measured their prefrontal activation by using near-infrared spectroscopy. We used movie stimuli that could robustly induce a positive affect, and the results for viewing own versus unfamiliar infants showed that own-infant viewing elicited increased activations around the anterior part of the orbitofrontal cortex (OFC) in the mothers. Their response magnitude in that area was also correlated with the behavioral rating of the pleasant mood of infants. Furthermore, our study revealed that the infants' prefrontal activation around the anterior OFC is specific to viewing their mothers' smile. These results suggest the OFC's role in regulating and encoding the affect in attachment system and also show that infants share similar neuronal functions with mothers, associated with their bonds at 1 year of age. We further discussed infants' prefrontal activations and their implications for the development of the social brain network.
AB - Attachment between mothers and infants is the most primitive and primary form of human social relationship. Many reports have suggested that the orbitofrontal cortex (OFC) plays a significant role in this attachment; however, only a select few provide experimental neurophysiological evidence. In the present study, to determine the neural substrates underlying the social and emotional attachment between mothers and infants, we measured their prefrontal activation by using near-infrared spectroscopy. We used movie stimuli that could robustly induce a positive affect, and the results for viewing own versus unfamiliar infants showed that own-infant viewing elicited increased activations around the anterior part of the orbitofrontal cortex (OFC) in the mothers. Their response magnitude in that area was also correlated with the behavioral rating of the pleasant mood of infants. Furthermore, our study revealed that the infants' prefrontal activation around the anterior OFC is specific to viewing their mothers' smile. These results suggest the OFC's role in regulating and encoding the affect in attachment system and also show that infants share similar neuronal functions with mothers, associated with their bonds at 1 year of age. We further discussed infants' prefrontal activations and their implications for the development of the social brain network.
KW - Attachment
KW - Emotion
KW - Infant
KW - Near-infrared spectroscopy (NIRS)
KW - Orbitofrontal cortex
KW - Social cognition
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UR - http://www.scopus.com/inward/citedby.url?scp=58449106007&partnerID=8YFLogxK
U2 - 10.1093/cercor/bhn081
DO - 10.1093/cercor/bhn081
M3 - Article
C2 - 18515298
AN - SCOPUS:58449106007
SN - 1047-3211
VL - 19
SP - 284
EP - 292
JO - Cerebral Cortex
JF - Cerebral Cortex
IS - 2
ER -