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Preparation and separation of metallobacteriochlorophyll a by reversed-phase high-performance liquid chromatography

  • H. Inoue
  • , Y. Nonomura
  • , A. Ashizawa
  • , I. Tajima
  • , M. Nomura
  • , N. Nakamura
  • , N. Yoshioka

Research output: Contribution to journalArticlepeer-review

Abstract

Semi-preparative high-performance liquid chromatography has been used for the preparation of copper(II) bacteriochlorophyll a [Cu(II)-BCh]-a] and zinc(II) bacteriochlorophyll a [Zn(II)-BCh]-a]. Both compounds are separated on a reversed-phase Inertsil ODS-2 column using a mobile phase of acetone-methanol (25:75, v/v). The fractionated metallobacteriochlorophylls (M-Bchl-a) are identified by fast atom bombardment mass spectrometry. The spectroscopic parameters such as the wavelength of absorption maxima and the molar extinction coefficients are determined using pure M-Bchl-a obtained by preparative HPLC. The HPLC method proposed here has been demonstrated to be useful for the purification and determination of components of M-Bchl-a.

Original languageEnglish
Pages (from-to)361-364
Number of pages4
JournalChromatographia
Volume43
Issue number7-8
DOIs
Publication statusPublished - 1996

Keywords

  • Bacteriochlorophyll a
  • Column liquid chromatography
  • Copper(II) bacteriochlorophyll a
  • Zinc(II) bacteriochlorophyll a

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry
  • Organic Chemistry

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