Preparation of Monomethyl Ether Derivatives of (+)-,(—)- and (±)-Indenestrols A and B

Taiko Oda, Yoshihiro Sato

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


In order to evaluate the contribution of the two phenolic hydroxyl groups to the biological activities of indenestrols A (IA) and B (IB), monomethyl ether derivatives of IA and IB were prepared and each enantiomer was separated to > 99% purity by high-pressure liquid chromatography using a chiral column. The structures of the enantiomers were confirmed by proton and carbon-13 nuclear magnetic resonance and circular dichroism spectroscopic studies.

Original languageEnglish
Pages (from-to)1856-1859
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Issue number10
Publication statusPublished - 1993 Jan 1


  • circular dichroism
  • indenestrol A monomethyl ether
  • indenestrol B monomethyl ether
  • optical resolution

ASJC Scopus subject areas

  • General Chemistry
  • Drug Discovery


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