TY - GEN
T1 - Pressure-driven injection of charged solute molecules from micro to nanochannel
AU - Okamoto, Kazuma
AU - Kazoe, Yutaka
AU - Mawatari, Kazuma
AU - Kitamori, Takehiko
N1 - Funding Information:
This work was supported by JST CREST Grant Number JPMJCR14G1, Japan.
Publisher Copyright:
Copyright© (2018) by Chemical and Biological Microsystems Society.All rights reserved.
PY - 2018
Y1 - 2018
N2 - We revealed that 100% injection of solute molecules regardless of solute charges from micro to nanochannel, where the electrostatic interaction is dominant, is achieved utilizing MPa pressure-driven flow. Different injection rates depending on solute charges could be cancelled by the fluid drag on solute molecules. The results in this study provide important knowledge for conceptual design of nanofluidic devices for fL-analytical applications such as single cell/single molecule analysis.
AB - We revealed that 100% injection of solute molecules regardless of solute charges from micro to nanochannel, where the electrostatic interaction is dominant, is achieved utilizing MPa pressure-driven flow. Different injection rates depending on solute charges could be cancelled by the fluid drag on solute molecules. The results in this study provide important knowledge for conceptual design of nanofluidic devices for fL-analytical applications such as single cell/single molecule analysis.
KW - Electrostatic interaction
KW - Extended-nano space
KW - Nanochannel
KW - Nanofluidics
KW - Sampling
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M3 - Conference contribution
AN - SCOPUS:85061526773
T3 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
SP - 438
EP - 439
BT - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PB - Chemical and Biological Microsystems Society
T2 - 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Y2 - 11 November 2018 through 15 November 2018
ER -