Procalcitonin as an early diagnostic marker for ventriculoperitoneal shunt infections

Ryosuke Tomio, Takenori Akiyama, Shunsuke Shibao, Kazunari Yoshida

Research output: Contribution to journalReview articlepeer-review

10 Citations (Scopus)


Background: Procalcitonin (PCT) has been considered a more reliable marker than others because of its specificity for bacterial infection. Methods: Case report and review of the literature. Results: A 50-year-old male was diagnosed with subarachnoid hemorrhage, intraventricular hemorrhage, and intracerebral hemorrhage. We performed a ruptured aneurysm clipping and left unilateral external ventricular drainage. We also performed ventriculoperitoneal (VP) shunt placement in the course; however, VP shunt infection was indicated by fever, increased C-reactive protein concentration and leukocytosis. The cerebrospinal fluid culture showed methicillin-resistant Staphylococcus epidermidis but the serum PCT concentration was quite low. Conclusions: Although PCT is considered a more reliable serological marker of bacterial meningitis in several reports, the serum PCT concentration did not reflect the bacterial VP shunt infection that was present in our case.

Original languageEnglish
Pages (from-to)433-436
Number of pages4
JournalSurgical Infections
Issue number5
Publication statusPublished - 2013 Oct 1

ASJC Scopus subject areas

  • Surgery
  • Microbiology (medical)
  • Infectious Diseases


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