Radiotherapy for hepatocellular carcinoma: Clinicopathological study of seven autopsy cases

K. Aoki, N. Okazaki, S. Okada, H. Nose, M. Yoshimori, Y. Akine, S. Egawa, M. Sakamoto, S. Hirohashi

Research output: Contribution to journalArticlepeer-review

39 Citations (Scopus)


The clinical value of radiotherapy for hepatocellular carcinoma (total tumor dose: 50- 70 Gy) was evaluated in seven autopsied patients with nine tumors. A partial response as defined by the WHO criteria for chemotherapy was observed in three tumors (33%). Progressive and marked shrinkage of the noncancerous liver tissue within the irradiated field was also observed in all cases. Histological examination revealed viable cancer cells in all cases. These results indicate that local radiotherapy applying 50-70 Gy achieved some clinical benefit, but was not capable of curing hepatocellular carcinoma.

Original languageEnglish
Pages (from-to)427-431
Number of pages5
Issue number5
Publication statusPublished - 1994
Externally publishedYes


  • Hepatocellular carcinoma
  • Pathological analysis
  • Radiotherapy

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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