Ras oncoprotein induces CD44 cleavage through phosphoinositide 3-OH kinase and the Rho family of small G proteins

Medicine & Life Sciences

• Monomeric GTP-Binding Proteins 86%
• Oncogene Proteins 82%
• Phosphatidylinositol 3-Kinase 74%
• Cell Movement 45%
• Phosphoinositide-3 Kinase Inhibitors 26%
• Neoplasms 23%
• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 21%
• Membranes 21%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 21%
• Cell Adhesion Molecules 20%
• Mitogen-Activated Protein Kinase Kinases 19%
• Metalloproteases 19%
• Extracellular Matrix 15%

Chemical Compounds

• Phosphoinositide 100%
• Cleavage 50%
• Protein 30%
• LY294002 14%
• Hyaluronate 11%
• Surface 2%