Rational design of pH-responsive near-infrared spirocyclic cyanines: the effects of substituents and the external environment

Akihiro Sakama, Hyemin Seo, Joji Hara, Yutaka Shindo, Yuma Ikeda, Kotaro Oka, Daniel Citterio, Yuki Hiruta

Research output: Contribution to journalArticlepeer-review

Abstract

pH-responsive spirocyclic cyanine dyes were designed and synthesized. The equilibrium constant for cyclization (pKcycl) could be rationally controlled by changing the nucleophilic moiety and the side chains. Encapsulation in polymeric micelles inhibited the H-aggregation of the dye, and the pKcycl could be shifted according to the amphiphilic polymer employed.

Original languageEnglish
Pages (from-to)5984-5987
Number of pages4
JournalChemical Communications
Volume60
Issue number46
DOIs
Publication statusPublished - 2024 May 13

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Catalysis
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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