Recent treatments of interstitial lung disease with systemic sclerosis

Hidekata Yasuoka

doi:10.4137/CCRPM.S23315

Recent treatments of interstitial lung disease with systemic sclerosis

Hidekata Yasuoka

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Systemic sclerosis (SSc) is a disorder characterized by immune dysfunction, microvascular injury, and fibrosis. Organ involvement in patients with SSc is variable; however, pulmonary involvement occurs in up to 90% of patients with SSc. Interstitial lung disease (ILD) is a major cause of mortality and, thus, a major determinant in the prognosis of patients with SSc. This review summarizes current findings about the characteristics of ILD in patients with SSc, selection of patients with SSc-ILD who are candidates for the treatment, and current treatment options.

Original language	English
Pages (from-to)	97-110
Number of pages	14
Journal	Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine
Volume	9
DOIs	https://doi.org/10.4137/CCRPM.S23315
Publication status	Published - 2016 Jan 19

Keywords

Interstitial lung disease
Pulmonary hypertension
Systemic sclerosis

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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10.4137/CCRPM.S23315

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abstract = "Systemic sclerosis (SSc) is a disorder characterized by immune dysfunction, microvascular injury, and fibrosis. Organ involvement in patients with SSc is variable; however, pulmonary involvement occurs in up to 90% of patients with SSc. Interstitial lung disease (ILD) is a major cause of mortality and, thus, a major determinant in the prognosis of patients with SSc. This review summarizes current findings about the characteristics of ILD in patients with SSc, selection of patients with SSc-ILD who are candidates for the treatment, and current treatment options.",

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N2 - Systemic sclerosis (SSc) is a disorder characterized by immune dysfunction, microvascular injury, and fibrosis. Organ involvement in patients with SSc is variable; however, pulmonary involvement occurs in up to 90% of patients with SSc. Interstitial lung disease (ILD) is a major cause of mortality and, thus, a major determinant in the prognosis of patients with SSc. This review summarizes current findings about the characteristics of ILD in patients with SSc, selection of patients with SSc-ILD who are candidates for the treatment, and current treatment options.

AB - Systemic sclerosis (SSc) is a disorder characterized by immune dysfunction, microvascular injury, and fibrosis. Organ involvement in patients with SSc is variable; however, pulmonary involvement occurs in up to 90% of patients with SSc. Interstitial lung disease (ILD) is a major cause of mortality and, thus, a major determinant in the prognosis of patients with SSc. This review summarizes current findings about the characteristics of ILD in patients with SSc, selection of patients with SSc-ILD who are candidates for the treatment, and current treatment options.

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Recent treatments of interstitial lung disease with systemic sclerosis

Abstract

Keywords

ASJC Scopus subject areas

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