Regenerative medicine and stem cell based drug discovery

Kazuhiro Sakurada, Fiona M. McDonald, Fumiki Shimada

Research output: Contribution to journalReview articlepeer-review

37 Citations (Scopus)

Abstract

As William Shakespeare beautifully described, increasing age often causes loss of tissue and organ function. The increase in average life expectancy in many countries is generating an aging society and an increase in age-related health problems. Regenerative medicine is expected to be a powerful actor in this drama, and stem cell technology may hold the key to the development of innovative treatments for acute and chronic degenerative conditions. This Review surveys the present situation and some future prospects for regenerative medicine and stem cell based drug discovery.

Original languageEnglish
Pages (from-to)5718-5738
Number of pages21
JournalAngewandte Chemie - International Edition
Volume47
Issue number31
DOIs
Publication statusPublished - 2008 Jul 21
Externally publishedYes

Keywords

  • Cytokines
  • Growth factors
  • Regenerative medicine
  • Stem cells

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry

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