Regenerative medicine in cardiology

Tomohiro Manabe, Keiichi Fukuda

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)


Emerging evidence indicates that cardiomyocytes can be regenerated from embryonic stem cells, adult mesenchymal stem cells, and cardiac side population cells (cardiac stem cells). When these cells were injected into diseased hearts, indices of cardiac function improved. There are ethical difficulties involved in the use of embryonic stem cells. The ratio of differentiation into cardiomyocytes is still relatively low at present. Transplantation of regenerated cardiomyocytes or stem cells, however, will become a future therapy for severe heart failure.

Original languageEnglish
Pages (from-to)454-458
Number of pages5
JournalNippon Geka Gakkai zasshi
Issue number8
Publication statusPublished - 2004 Aug

ASJC Scopus subject areas

  • General Medicine


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