@article{d91d8a5ac6d545958cee94db647e7302,
title = "Relation between number of teeth, malnutrition, and 3-year mortality in elderly individuals ≥85 years",
abstract = "Objective: The number of teeth has been shown to affect mortality. However, it is unclear why the number of teeth is associated with mortality. We focused on the number of teeth and malnutrition and examined whether these differences affect 3-year all-cause mortality among very elderly individuals. Methods: This analysis was conducted using data from the Tokyo Oldest Old Survey on Total Health study. Altogether 513 participants ≥85 years were categorized based on remaining teeth (0, 1–7, 8–18, ≥19). All-cause mortality was determined by calculating the cumulative 3-year survival rate according to the remaining number of teeth and the presence/absence of malnutrition. Further, hazard ratios (HRs) were analyzed using Cox regression analyses. Results: No difference was observed according to the number of teeth (p = 0.638), but the presence/absence of malnutrition was significantly associated with mortality (p < 0.001). Malnutrition was independently associated with higher HRs, even after adjusting for confounding factors associated with mortality. (HR: 2.315, 95% CI: 1.431–3.746). Additionally, adjusting for the number of teeth, HR remained significant (HR: 2.365, 95% CI: 1.449–3.853). Conclusion: In the very elderly, malnutrition—but not the number of teeth—was independently associated with 3-year all-cause mortality after adjusting for various health issues.",
keywords = "GLIM criteria, life expectancy, malnutrition, oral health, very elderly",
author = "Kensuke Nishio and Yasumichi Arai and Yukiko Abe and Michiyo Takayama and Mai Fukasawa and Daichi Oikawa and Tomoka Ito and Masaki Takatsu and Toshimitsu Iinuma",
note = "Funding Information: The financial support for this study was provided by the Grants‐in‐Aid for Scientific Research (C) (No. 22592347, 26463194, 20590706, 21590775, and 23617024) from the Japan Society for the Promotion of Science, by a grant from the Sato Fund, Nihon University School of Dentistry, by a grant from the Japan Health Foundation for the Prevention of Chronic Disease and the Improvement of QOL of Patients, by a grant from the Foundation for Total Health Promotion, by The Univers Foundation, and by the Chiyoda Mutual Life Foundation Funding Information: The financial support for this study was provided by the Grants-in-Aid for Scientific Research (C) (No. 22592347, 26463194, 20590706, 21590775, and 23617024) from the Japan Society for the Promotion of Science, by a grant from the Sato Fund, Nihon University School of Dentistry, by a grant from the Japan Health Foundation for the Prevention of Chronic Disease and the Improvement of QOL of Patients, by a grant from the Foundation for Total Health Promotion, by The Univers Foundation, and by the Chiyoda Mutual Life Foundation We would like to express our sincere gratitude to all the participants for their time providing us the valuable information and Miho Shimura for her kind assistance. In addition to the authors, the following contributed to data acquisition as TOOTH investigators: Ken Yamamura, MD, PhD; Yoshinori Ebihara, MD, PhD; Kenichiro Shimizu, MD, PhD; Susumu Nakazawa, MD; Kentaro Urata, DDS, PhD; Mitsuru Maruno, DDS, PhD; and Reio Ito, DDS, PhD. Publisher Copyright: {\textcopyright} 2021 The Authors. Oral Diseases published by Wiley Periodicals LLC.",
year = "2023",
month = mar,
doi = "10.1111/odi.14023",
language = "English",
volume = "29",
pages = "827--835",
journal = "Oral Diseases",
issn = "1354-523X",
publisher = "Wiley-Blackwell",
number = "2",
}
