Relationship between BMI and all-cause mortality in Japan: NIPPON DATA80

Atsushi Hozawa; Tomonori Okamura; Izumi Oki; Yoshitaka Murakami; Takashi Kadowaki; Koshi Nakamura; Naomi Miyamatsu; Takehito Hayakawa; Yoshikuni Kita; Yosikazu Nakamura; Yasuyuki Nakamura; Robert D. Abbott; Akira Okayama; Hirotsugu Ueshima; Osamu Iimura; Teruo Omae; Kazuo Ueda; Hiroshi Yanagawa; Hiroshi Horibe; Kazunori Kodama; Fumiyoshi Kasagi; Shinichi Tanihara; Shigeyuki Saito; Kiyomi Sakata; Fumihiko Kakuno; Toshihiro Takeuchi; Mitsuru Hasebe; Fumitsugu Kusano; Takahisa Kawamoto; Masumi Minowa; Minoru Iida; Tsutomu Hashimoto; Shigemichi Tanaka; Atsushi Terao; Katsuhiko Kawaminami; Koryo Sawai; Shigeo Shibata

doi:10.1038/oby.2008.237

Relationship between BMI and all-cause mortality in Japan: NIPPON DATA80

Atsushi Hozawa, Tomonori Okamura, Izumi Oki, Yoshitaka Murakami, Takashi Kadowaki, Koshi Nakamura, Naomi Miyamatsu, Takehito Hayakawa, Yoshikuni Kita, Yosikazu Nakamura, Yasuyuki Nakamura, Robert D. Abbott, Akira Okayama, Hirotsugu Ueshima, Osamu Iimura, Teruo Omae, Kazuo Ueda, Hiroshi Yanagawa, Hiroshi Horibe, Kazunori KodamaFumiyoshi Kasagi, Shinichi Tanihara, Shigeyuki Saito, Kiyomi Sakata, Fumihiko Kakuno, Toshihiro Takeuchi, Mitsuru Hasebe, Fumitsugu Kusano, Takahisa Kawamoto, Masumi Minowa, Minoru Iida, Tsutomu Hashimoto, Shigemichi Tanaka, Atsushi Terao, Katsuhiko Kawaminami, Koryo Sawai, Shigeo Shibata

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

As body composition in Asian populations is largely different from Western populations, a healthy BMI could also differ between the two populations. Thus, further study is needed to determine whether a healthy BMI in Asians should be lower than Western populations, as recommended by the World Health Organization (WHO). We investigated the relationship between BMI and mortality in a sample of 8,924 Japanese men and women without stroke or heart disease. During 19 years of follow-up, 1,718 deaths were observed. We found a U-shaped relationship between BMI and fatal events. Risk of total mortality was highest in participants with BMI <18.5 kg/m² and lowest in participants with BMI 23.0-24.9 kg/m². These findings persisted even after excluding the first 5 years of follow-up with a focus on healthy participants who never smoked, were aged <70 years, and had total cholesterol (TC) levels ≥4.1 mmol/l (N = 3712). For both the full sample and healthy participants, all-cause mortality risk did not differ between BMI ranges 21.0-22.9 and 23.0-24.9 kg/m². Our findings do not support the recent WHO implications that BMIs <23.0 kg/m² is healthy for Asians. Therefore, further studies are needed to identify an optimal BMI range for Asia.

Original language	English
Pages (from-to)	1714-1717
Number of pages	4
Journal	Obesity
Volume	16
Issue number	7
DOIs	https://doi.org/10.1038/oby.2008.237
Publication status	Published - 2008 Jul
Externally published	Yes

ASJC Scopus subject areas

Medicine (miscellaneous)
Endocrinology, Diabetes and Metabolism
Endocrinology
Nutrition and Dietetics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/oby.2008.237

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Hozawa, A., Okamura, T., Oki, I., Murakami, Y., Kadowaki, T., Nakamura, K., Miyamatsu, N., Hayakawa, T., Kita, Y., Nakamura, Y., Nakamura, Y., Abbott, R. D., Okayama, A., Ueshima, H., Iimura, O., Omae, T., Ueda, K., Yanagawa, H., Horibe, H., ... Shibata, S. (2008). Relationship between BMI and all-cause mortality in Japan: NIPPON DATA80. Obesity, 16(7), 1714-1717. https://doi.org/10.1038/oby.2008.237

Hozawa, A, Okamura, T, Oki, I, Murakami, Y, Kadowaki, T, Nakamura, K, Miyamatsu, N, Hayakawa, T, Kita, Y, Nakamura, Y, Nakamura, Y, Abbott, RD, Okayama, A, Ueshima, H, Iimura, O, Omae, T, Ueda, K, Yanagawa, H, Horibe, H, Kodama, K, Kasagi, F, Tanihara, S, Saito, S, Sakata, K, Kakuno, F, Takeuchi, T, Hasebe, M, Kusano, F, Kawamoto, T, Minowa, M, Iida, M, Hashimoto, T, Tanaka, S, Terao, A, Kawaminami, K, Sawai, K & Shibata, S 2008, 'Relationship between BMI and all-cause mortality in Japan: NIPPON DATA80', Obesity, vol. 16, no. 7, pp. 1714-1717. https://doi.org/10.1038/oby.2008.237

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title = "Relationship between BMI and all-cause mortality in Japan: NIPPON DATA80",

abstract = "As body composition in Asian populations is largely different from Western populations, a healthy BMI could also differ between the two populations. Thus, further study is needed to determine whether a healthy BMI in Asians should be lower than Western populations, as recommended by the World Health Organization (WHO). We investigated the relationship between BMI and mortality in a sample of 8,924 Japanese men and women without stroke or heart disease. During 19 years of follow-up, 1,718 deaths were observed. We found a U-shaped relationship between BMI and fatal events. Risk of total mortality was highest in participants with BMI <18.5 kg/m2 and lowest in participants with BMI 23.0-24.9 kg/m2. These findings persisted even after excluding the first 5 years of follow-up with a focus on healthy participants who never smoked, were aged <70 years, and had total cholesterol (TC) levels ≥4.1 mmol/l (N = 3712). For both the full sample and healthy participants, all-cause mortality risk did not differ between BMI ranges 21.0-22.9 and 23.0-24.9 kg/m2. Our findings do not support the recent WHO implications that BMIs <23.0 kg/m2 is healthy for Asians. Therefore, further studies are needed to identify an optimal BMI range for Asia.",

author = "Atsushi Hozawa and Tomonori Okamura and Izumi Oki and Yoshitaka Murakami and Takashi Kadowaki and Koshi Nakamura and Naomi Miyamatsu and Takehito Hayakawa and Yoshikuni Kita and Yosikazu Nakamura and Yasuyuki Nakamura and Abbott, {Robert D.} and Akira Okayama and Hirotsugu Ueshima and Osamu Iimura and Teruo Omae and Kazuo Ueda and Hiroshi Yanagawa and Hiroshi Horibe and Kazunori Kodama and Fumiyoshi Kasagi and Shinichi Tanihara and Shigeyuki Saito and Kiyomi Sakata and Fumihiko Kakuno and Toshihiro Takeuchi and Mitsuru Hasebe and Fumitsugu Kusano and Takahisa Kawamoto and Masumi Minowa and Minoru Iida and Tsutomu Hashimoto and Shigemichi Tanaka and Atsushi Terao and Katsuhiko Kawaminami and Koryo Sawai and Shigeo Shibata",

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T1 - Relationship between BMI and all-cause mortality in Japan

T2 - NIPPON DATA80

AU - Hozawa, Atsushi

AU - Okamura, Tomonori

AU - Oki, Izumi

AU - Murakami, Yoshitaka

AU - Kadowaki, Takashi

AU - Nakamura, Koshi

AU - Miyamatsu, Naomi

AU - Hayakawa, Takehito

AU - Kita, Yoshikuni

AU - Nakamura, Yosikazu

AU - Nakamura, Yasuyuki

AU - Abbott, Robert D.

AU - Okayama, Akira

AU - Ueshima, Hirotsugu

AU - Iimura, Osamu

AU - Omae, Teruo

AU - Ueda, Kazuo

AU - Yanagawa, Hiroshi

AU - Horibe, Hiroshi

AU - Kodama, Kazunori

AU - Kasagi, Fumiyoshi

AU - Tanihara, Shinichi

AU - Saito, Shigeyuki

AU - Sakata, Kiyomi

AU - Kakuno, Fumihiko

AU - Takeuchi, Toshihiro

AU - Hasebe, Mitsuru

AU - Kusano, Fumitsugu

AU - Kawamoto, Takahisa

AU - Minowa, Masumi

AU - Iida, Minoru

AU - Hashimoto, Tsutomu

AU - Tanaka, Shigemichi

AU - Terao, Atsushi

AU - Kawaminami, Katsuhiko

AU - Sawai, Koryo

AU - Shibata, Shigeo

PY - 2008/7

Y1 - 2008/7

N2 - As body composition in Asian populations is largely different from Western populations, a healthy BMI could also differ between the two populations. Thus, further study is needed to determine whether a healthy BMI in Asians should be lower than Western populations, as recommended by the World Health Organization (WHO). We investigated the relationship between BMI and mortality in a sample of 8,924 Japanese men and women without stroke or heart disease. During 19 years of follow-up, 1,718 deaths were observed. We found a U-shaped relationship between BMI and fatal events. Risk of total mortality was highest in participants with BMI <18.5 kg/m2 and lowest in participants with BMI 23.0-24.9 kg/m2. These findings persisted even after excluding the first 5 years of follow-up with a focus on healthy participants who never smoked, were aged <70 years, and had total cholesterol (TC) levels ≥4.1 mmol/l (N = 3712). For both the full sample and healthy participants, all-cause mortality risk did not differ between BMI ranges 21.0-22.9 and 23.0-24.9 kg/m2. Our findings do not support the recent WHO implications that BMIs <23.0 kg/m2 is healthy for Asians. Therefore, further studies are needed to identify an optimal BMI range for Asia.

AB - As body composition in Asian populations is largely different from Western populations, a healthy BMI could also differ between the two populations. Thus, further study is needed to determine whether a healthy BMI in Asians should be lower than Western populations, as recommended by the World Health Organization (WHO). We investigated the relationship between BMI and mortality in a sample of 8,924 Japanese men and women without stroke or heart disease. During 19 years of follow-up, 1,718 deaths were observed. We found a U-shaped relationship between BMI and fatal events. Risk of total mortality was highest in participants with BMI <18.5 kg/m2 and lowest in participants with BMI 23.0-24.9 kg/m2. These findings persisted even after excluding the first 5 years of follow-up with a focus on healthy participants who never smoked, were aged <70 years, and had total cholesterol (TC) levels ≥4.1 mmol/l (N = 3712). For both the full sample and healthy participants, all-cause mortality risk did not differ between BMI ranges 21.0-22.9 and 23.0-24.9 kg/m2. Our findings do not support the recent WHO implications that BMIs <23.0 kg/m2 is healthy for Asians. Therefore, further studies are needed to identify an optimal BMI range for Asia.

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Relationship between BMI and all-cause mortality in Japan: NIPPON DATA80

Abstract

ASJC Scopus subject areas

UN SDGs

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