Remitting seronegative symmetrical synovitis with pitting edema (RS3PE)

M. Sano, S. Okamoto, T. Yamawaki, M. Sakauchi, T. Meguro, T. Takita, K. Narushima, N. Suzuki

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


We report 2 elderly patients who present with a relatively acute onset of a severe symmetrical synovitis affecting the flexor digitorum tendon sheaths and wrist joints with pitting edema of the dorsum of both hands. These patients were seronegative for rheumatoid factor and responded to treatment with low dose predonisone (10 mg daily) without relapse. These presenting features were closely linked with the RS3PE syndrome originally described by McCarty.

Original languageEnglish
Pages (from-to)493-498
Number of pages6
Issue number3
Publication statusPublished - 1997
Externally publishedYes


  • Pitting edema
  • Purpura annularis teleangiectodes Majocchi
  • RSPE syndrome
  • Rheumatoid arthritis
  • Seronegative

ASJC Scopus subject areas

  • Rheumatology


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