Rhodium-Catalyzed β-Acylalkylation of Allylbenzene Derivatives with Allyl Alcohols via C-C Bond Cleavage

Soya Ishikawa, Ryo Togashi, Ryosuke Ueda, Shunsuke Onodera, Takuya Kochi, Fumitoshi Kakiuchi

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We report here a deallylative β-acylalkylation reaction of allylbenzene derivatives with allyl alcohols in the presence of Cp*Rh catalysts. Allylbenzenes possessing pyridyl and pyrazolyl directing groups were converted to β-aryl ketones via the cleavage of C(aryl)-C(allyl) bonds. Synthesis of a quinoline derivative from a β-aryl ketone product bearing a pyrazolyl group was also achieved.

Original languageEnglish
Pages (from-to)3313-3320
Number of pages8
JournalJournal of Organic Chemistry
Volume88
Issue number5
DOIs
Publication statusPublished - 2023 Mar 3

ASJC Scopus subject areas

  • Organic Chemistry

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