RNA-binding proteins as regulators of gene expression

Haruhiko Siomi, Gideon Dreyfuss

Research output: Contribution to journalArticlepeer-review

232 Citations (Scopus)

Abstract

A plethora of post-transcriptional mechanisms are involved in essential steps in the pathway of genetic information expression in eukaryotes. These processes are specified by cis-acting signals on RNAs and are mediated by specific trans-acting factors, including RNA-binding proteins and small complementary RNAs. Recent information has begun to define the molecular mechanisms by which RNA-binding proteins recognize specific RNA sequences and influence the processing and function of RNA molecules.

Original languageEnglish
Pages (from-to)345-353
Number of pages9
JournalCurrent Opinion in Genetics and Development
Volume7
Issue number3
DOIs
Publication statusPublished - 1997 Jun
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

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