Abstract
Atherosclerosis is recognized as an inflammatory condition of the vessel wall, characterized by accumulation of inflammatory cells such as macrophages and T cells. There are accumulating evidences that chemokines, cytokines, and lipid mediators coordinately modulate platelet- or leukocyte-endothelial cell interactions, and contribute to the maintenance of vascular homeostasis. This review focuses on the role of lipid mediators, especially those derived from polyunsaturated fatty acids, in controlling vascular inflammation and the progression of atherosclerosis.
Original language | English |
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Pages (from-to) | 34-38 |
Number of pages | 5 |
Journal | Nippon rinsho. Japanese journal of clinical medicine |
Volume | 69 |
Issue number | 1 |
Publication status | Published - 2011 Jan 1 |
Externally published | Yes |
ASJC Scopus subject areas
- Medicine(all)