Roles of Tbx4 in the lung mesenchyme for airway and vascular development

Keiko Uchida; Yu Yoshida; Kazuki Kodo; Hiroyuki Yamagishi

doi:10.1007/978-981-15-1185-1_8

Roles of Tbx4 in the lung mesenchyme for airway and vascular development

Keiko Uchida, Yu Yoshida, Kazuki Kodo, Hiroyuki Yamagishi

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Citations (Scopus)

Abstract

The T-box family genes are evolutionarily conserved transcription factors. In particular, Tbx4 and Tbx5 are closely conserved and play crucial roles in development and organogenesis. Tbx4 is essential for hindlimb and allantoic vessel formation [1]. It is also highly expressed in the lung mesenchyme (Fig. 8.1), initially expressed at embryonic day (E) 9.25 and later expressed throughout murine embryogenesis [2].

Original language	English
Title of host publication	Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension
Publisher	Springer Singapore
Pages	79-81
Number of pages	3
ISBN (Electronic)	9789811511851
ISBN (Print)	9789811511844
DOIs	https://doi.org/10.1007/978-981-15-1185-1_8
Publication status	Published - 2020 Jan 1

Keywords

Lung
Mesenchyme
Transcription factor
Vascular development

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-981-15-1185-1_8

Cite this

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AU - Kodo, Kazuki

AU - Yamagishi, Hiroyuki

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Y1 - 2020/1/1

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AB - The T-box family genes are evolutionarily conserved transcription factors. In particular, Tbx4 and Tbx5 are closely conserved and play crucial roles in development and organogenesis. Tbx4 is essential for hindlimb and allantoic vessel formation [1]. It is also highly expressed in the lung mesenchyme (Fig. 8.1), initially expressed at embryonic day (E) 9.25 and later expressed throughout murine embryogenesis [2].

KW - Lung

KW - Mesenchyme

KW - Transcription factor

KW - Vascular development

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BT - Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension

PB - Springer Singapore

ER -

Roles of Tbx4 in the lung mesenchyme for airway and vascular development

Abstract

Keywords

ASJC Scopus subject areas

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