Segmentation of magnetic resonance images to construct human head model for diffuse optical imaging

Kazuki Kurihara, Hiroshi Kawaguchi, Yosuke Takahashi, Takayuki Obata, Eiji Okada

    Research output: Chapter in Book/Report/Conference proceedingConference contribution


    The brain activation image obtained by diffuse optical tomography (DOT) is obtained by solving inverse problem using the spatial sensitivity profile (SSP). The SSP can be obtained from the analysis of the light propagation using threedimensional head models. The head model is based upon segmented magnetic resonance (MR) image and there are several types of software based on binarization for segmentation of MR head images. We segmented superficial tissues which effect the light propagation in human head from MR images acquired with FATSAT and FIESTA pulse sequences by using region growing algorithm and morphological operation to facilitate the construction of the individual head models for DOT. The pixel intensity distribution of these images has appropriate characteristics to extract the superficial tissues by using algorithm based on binarization. The result of extraction was compared with the extraction from T2-weighted image which is commonly used to extract superficial tissues. The result of extraction from FATSAT or FIESTA image agree well with ground truth determined by manual segmentation.

    Original languageEnglish
    Title of host publicationDiffuse Optical Imaging III
    Publication statusPublished - 2011 Jul 28
    EventDiffuse Optical Imaging III - Munich, Germany
    Duration: 2011 May 222011 May 24

    Publication series

    NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
    ISSN (Print)1605-7422


    OtherDiffuse Optical Imaging III


    • DOT
    • FATSAT
    • FIESTA
    • MR image
    • head model
    • light propagation
    • pulse sequence
    • segmentation

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Biomaterials
    • Atomic and Molecular Physics, and Optics
    • Radiology Nuclear Medicine and imaging


    Dive into the research topics of 'Segmentation of magnetic resonance images to construct human head model for diffuse optical imaging'. Together they form a unique fingerprint.

    Cite this