Serrated adenoma developing into advanced colon cancer in 2 years

Takeyoshi Yamauchi, Masahiko Watanabe, Hirotoshi Hasegawa, Seiichiro Yamamoto, Takashi Endo, Yasuo Kabeshima, Kyoko Yorozuya, Kentaro Yamamoto, Masaki Kitajima

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


We report the case of a 76-year-old woman with a flat elevated lesion (laterally spreading tumor; LST) in the transverse colon that had been identified 2 years before the current presentation. Pathologically, the lesion had been diagnosed asia serrated adenoma with severe dysplasia. The patient had refused endoscopic resection because she was afraid of the risk of colonic perforation; she did not come to follow-up until 2 years after the diagnosis, when she had advanced colon cancer in the transverse colon where the LST had been detected. Histopathological examination confirmed a poorly differentiated adenocarcinoma with no adenomatous component such as had been found in the LST lesion.

Original languageEnglish
Pages (from-to)467-470
Number of pages4
JournalJournal of gastroenterology
Issue number6
Publication statusPublished - 2002 Jan 1


  • Adenoma-carcinoma sequence
  • De novo
  • Laterally spreading tumor (LST)
  • Serrated adenoma

ASJC Scopus subject areas

  • Gastroenterology


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