Silver-catalyzed carboxylation

K. Sekine, T. Yamada

Research output: Contribution to journalReview articlepeer-review

234 Citations (Scopus)


Silver-catalyzed reactions are some of the important methodologies in organic chemistry. Since 2007, a new application of silver catalysts has been emerging. For the sequential carboxylation and cyclization of alkyne derivatives, such as propargyl alcohols and amines, using carbon dioxide, silver catalysts show significant reactivity under mild conditions unlike other transition metals. These developments have received much attention for the effective utilization of carbon dioxide in organic chemistry to synthesize heterocyclic compounds. Related silver-catalyzed C-C bond forming reactions with carbon dioxide have also provided the synthetic methods of the corresponding carboxylic acid derivatives. In this review, the recent studies of the silver-catalyzed carboxylation reactions using carbon dioxide are described.

Original languageEnglish
Pages (from-to)4524-4532
Number of pages9
JournalChemical Society Reviews
Issue number16
Publication statusPublished - 2016 Aug 21

ASJC Scopus subject areas

  • General Chemistry


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