Small RNAs: Artificial piRNAs for transcriptional silencing

Takamasa Hirano; Haruhiko Siomi

doi:10.1016/j.cub.2015.02.009

Small RNAs: Artificial piRNAs for transcriptional silencing

Takamasa Hirano, Haruhiko Siomi

Department of Molecular Biology

Research output: Contribution to journal › Short survey › peer-review

3 Citations (Scopus)

Abstract

Technologies have been developed in animal germ cells that produce artificial piRNAs from transgenes in piRNA clusters to silence target genes by cleaving their transcripts. A new study provides a simple way to generate artificial piRNAs to direct de novo DNA methylation in mice.

Original language	English
Pages (from-to)	R280-R283
Journal	Current Biology
Volume	25
Issue number	7
DOIs	https://doi.org/10.1016/j.cub.2015.02.009
Publication status	Published - 2015

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Agricultural and Biological Sciences(all)

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10.1016/j.cub.2015.02.009

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title = "Small RNAs: Artificial piRNAs for transcriptional silencing",

abstract = "Technologies have been developed in animal germ cells that produce artificial piRNAs from transgenes in piRNA clusters to silence target genes by cleaving their transcripts. A new study provides a simple way to generate artificial piRNAs to direct de novo DNA methylation in mice.",

author = "Takamasa Hirano and Haruhiko Siomi",

year = "2015",

doi = "10.1016/j.cub.2015.02.009",

language = "English",

volume = "25",

pages = "R280--R283",

journal = "Current Biology",

issn = "0960-9822",

publisher = "Cell Press",

number = "7",

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T1 - Small RNAs

T2 - Artificial piRNAs for transcriptional silencing

AU - Hirano, Takamasa

AU - Siomi, Haruhiko

PY - 2015

Y1 - 2015

N2 - Technologies have been developed in animal germ cells that produce artificial piRNAs from transgenes in piRNA clusters to silence target genes by cleaving their transcripts. A new study provides a simple way to generate artificial piRNAs to direct de novo DNA methylation in mice.

AB - Technologies have been developed in animal germ cells that produce artificial piRNAs from transgenes in piRNA clusters to silence target genes by cleaving their transcripts. A new study provides a simple way to generate artificial piRNAs to direct de novo DNA methylation in mice.

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U2 - 10.1016/j.cub.2015.02.009

DO - 10.1016/j.cub.2015.02.009

M3 - Short survey

C2 - 25829012

AN - SCOPUS:84932613328

SN - 0960-9822

VL - 25

SP - R280-R283

JO - Current Biology

JF - Current Biology

IS - 7

ER -

Small RNAs: Artificial piRNAs for transcriptional silencing

Abstract

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