Solitary hepatic lymphangioma: Report of a case

Takuya Matsumoto, Hidenori Ojima, Yuri Akishima-Fukasawa, Nobuyoshi Hiraoka, Hiroaki Onaya, Kazuaki Shimada, Yasunori Mizuguchi, Shintaro Sakurai, Toshiharu Ishii, Tomoo Kosuge, Yae Kanai

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


A 52-year-old woman presented with upper abdominal pain. Abdominal ultrasonography showed a 4-cm well-defined mass containing solid and cystic components in segment IV of the liver, and contrast-enhanced T1-weighted magnetic resonance imaging revealed heterogeneous enhancement within the tumor, indicating a solid or fibrous component. There were no cystic lesions in any other organs. A partial hepatectomy was performed, based on a preoperative diagnosis of sclerosing hemangioma and biliary cystadenoma or cystadenocarcinoma. Pathologically, the tumor appeared to be a multilocular and cystic lesion lined by attenuated endothelial- like cells with no atypia. Immunohistochemistry demonstrated the endothelial-like cells to be positive for the lymphatic-specific markers D2-40, LYVE-1, and Prox-1, which proved helpful for confirming the diagnosis as solitary hepatic lymphangioma. This case is presented with details of the pathologic and radiologic findings, because solitary hepatic lymphangioma is an extremely rare tumor and no previous reports have provided details of the immunohistochemical characteristics.

Original languageEnglish
Pages (from-to)883-889
Number of pages7
JournalSurgery today
Issue number9
Publication statusPublished - 2010 Sept
Externally publishedYes


  • D2-40
  • Hemangioma
  • LYVE-1
  • Prox-1
  • Solitary hepatic lymphangioma

ASJC Scopus subject areas

  • Surgery


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