Solvent effect on ruthenium catalyzed dihydroxylation

Tony K.M. Shing, Eric K.W. Tam

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)


The effect of different solvents on flash dihydroxylation is compared and for the first time, the replacement of ethyl acetate with acetone was shown to give a successful, catalytic cis-dihydroxylation of the alkene moiety in cholesteryl acetate and the ruthenium catalytic cycle could be maintained by methanesulfonamide in the absence of acetonitrile.

Original languageEnglish
Pages (from-to)2179-2180
Number of pages2
JournalTetrahedron Letters
Issue number11
Publication statusPublished - 1999 Mar 12

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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