@article{1b0478e7142444388ee8582454944f62,
title = "Spontaneous differentiation of human mesenchymal stem cells on poly-lactic-co- glycolic acid nano-fiber scaffold",
abstract = "Mesenchymal stem cells (MSCs) have immunosuppressive activity and can differentiate into bone and cartilage; and thus seem ideal for treatment of rheumatoid arthritis (RA). Here, we investigated the osteogenesis and chondrogenesis potentials of MSCs seeded onto nano-fiber scaffolds (NFs) in vitro and possible use for the repair of RA-affected joints.",
author = "Koshiro Sonomoto and Kunihiro Yamaoka and Hiroaki Kaneko and Kaoru Yamagata and Kei Sakata and Xiangmei Zhang and Masahiro Kondo and Yukichi Zenke and Ken Sabanai and Shingo Nakayamada and Akinori Sakai and Yoshiya Tanaka",
note = "Funding Information: The authors of this manuscript have read the journal's policy and have the following competing interests: YT has received consulting fees, speaking fees, and/or honoraria from Abbvie, Daiichi-Sankyo, Chugai, Takeda, Mitsubishi-Tanabe, Bristol-Myers, Astellas, Eisai, Janssen, Pfizer, Asahi-kasei, Eli Lilly, GlaxoSmithKline, UCB, Teijin, MSD, and Santen. YT has also received research grants from Mitsubishi-Tanabe, Takeda, Chugai, Astellas, Eisai, Taisho-Toyama, Kyowa-Kirin, Abbvie, and Bristol-Myers. KYamaoka has received consultant fees and speaking fees from Pfizer, Chugai, Mitsubishi-Tanabe, Takeda, GlaxoSmithKline, Nippon Shinyaku, Eli Lilly, Janssen, Eisai, Astellas, Acterlion. HK is employee of Teijin Limited. K. Sakata and MK are employees of Mitsubishi-Tanabe. This does not alter the authors{\textquoteright} adherence to PLOS ONE policies on sharing data and materials. AS has received consulting fees, speaking fees, and/or honoraria from Astellas, Chugai, Daiichi-Sankyo, and Taisho-Toyama. The other authors declare no conflicts of interest. Publisher Copyright: {\textcopyright} 2016 Sonomoto et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.",
year = "2016",
month = apr,
doi = "10.1371/journal.pone.0153231",
language = "English",
volume = "11",
journal = "PloS one",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "4",
}