Structural and conformational studies on euphohelioscopins A and B and related diterpenes

Yoshikazu Shizuri; Seiji Kosemura; Jiro Ohtsuka; Yukimasa Terada; Shosuke Yamamura

doi:10.1016/S0040-4039(00)81986-3

Structural and conformational studies on euphohelioscopins A and B and related diterpenes

Yoshikazu Shizuri, Seiji Kosemura, Jiro Ohtsuka, Yukimasa Terada, Shosuke Yamamura

Faculty of Law

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Two new toxic diterpenes (euphohelioscopins A and B) and two euphoscopin-type ones (euphoscopins C and D) have been isolated from the plant Euphorbia helioscopia L., and their stereostructures and conformations also been elucidated on the basis of their spectral data and some chemical evidence, together with successful application of molecular mechanics calculations to such flexible molecules as described herein.

Original language	English
Pages (from-to)	2577-2580
Number of pages	4
Journal	Tetrahedron Letters
Volume	24
Issue number	25
DOIs	https://doi.org/10.1016/S0040-4039(00)81986-3
Publication status	Published - 1983

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)81986-3

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abstract = "Two new toxic diterpenes (euphohelioscopins A and B) and two euphoscopin-type ones (euphoscopins C and D) have been isolated from the plant Euphorbia helioscopia L., and their stereostructures and conformations also been elucidated on the basis of their spectral data and some chemical evidence, together with successful application of molecular mechanics calculations to such flexible molecules as described herein.",

author = "Yoshikazu Shizuri and Seiji Kosemura and Jiro Ohtsuka and Yukimasa Terada and Shosuke Yamamura",

year = "1983",

doi = "10.1016/S0040-4039(00)81986-3",

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T1 - Structural and conformational studies on euphohelioscopins A and B and related diterpenes

AU - Shizuri, Yoshikazu

AU - Kosemura, Seiji

AU - Ohtsuka, Jiro

AU - Terada, Yukimasa

AU - Yamamura, Shosuke

PY - 1983

Y1 - 1983

N2 - Two new toxic diterpenes (euphohelioscopins A and B) and two euphoscopin-type ones (euphoscopins C and D) have been isolated from the plant Euphorbia helioscopia L., and their stereostructures and conformations also been elucidated on the basis of their spectral data and some chemical evidence, together with successful application of molecular mechanics calculations to such flexible molecules as described herein.

AB - Two new toxic diterpenes (euphohelioscopins A and B) and two euphoscopin-type ones (euphoscopins C and D) have been isolated from the plant Euphorbia helioscopia L., and their stereostructures and conformations also been elucidated on the basis of their spectral data and some chemical evidence, together with successful application of molecular mechanics calculations to such flexible molecules as described herein.

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 25

ER -

Structural and conformational studies on euphohelioscopins A and B and related diterpenes

Abstract

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