Structural and conformational studies on euphornin and related diterpenes

Yoshikazu Shizuri, Seiji Kosemura, Jiro Ohtsuka, Yukimasa Terada, Shosuke Yamamura, Shigeru Ohba, Masatoki Ito, Yoshihiko Saito

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


In addition to euphornin, three new toxic substances (euphornins A, B and C) have been isolated from the plant Euphorbia helioscopia L., and their absolute stereostructures also been elucidated on the basis of their spectral data and some chemical evidence together with an X-ray crystallographic analysis of the p-bromobenzoate derived from euphornin. Furthermore, their conformations have also been discussed.

Original languageEnglish
Pages (from-to)1155-1158
Number of pages4
JournalTetrahedron Letters
Issue number11
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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