Structural and conformational studies on euphornin and related diterpenes

Yoshikazu Shizuri; Seiji Kosemura; Jiro Ohtsuka; Yukimasa Terada; Shosuke Yamamura; Shigeru Ohba; Masatoki Ito; Yoshihiko Saito

doi:10.1016/S0040-4039(01)91548-5

Structural and conformational studies on euphornin and related diterpenes

Yoshikazu Shizuri, Seiji Kosemura, Jiro Ohtsuka, Yukimasa Terada, Shosuke Yamamura, Shigeru Ohba, Masatoki Ito, Yoshihiko Saito

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27 Citations (Scopus)

Abstract

In addition to euphornin, three new toxic substances (euphornins A, B and C) have been isolated from the plant Euphorbia helioscopia L., and their absolute stereostructures also been elucidated on the basis of their spectral data and some chemical evidence together with an X-ray crystallographic analysis of the p-bromobenzoate derived from euphornin. Furthermore, their conformations have also been discussed.

Original language	English
Pages (from-to)	1155-1158
Number of pages	4
Journal	Tetrahedron Letters
Volume	25
Issue number	11
DOIs	https://doi.org/10.1016/S0040-4039(01)91548-5
Publication status	Published - 1984

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(01)91548-5

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title = "Structural and conformational studies on euphornin and related diterpenes",

abstract = "In addition to euphornin, three new toxic substances (euphornins A, B and C) have been isolated from the plant Euphorbia helioscopia L., and their absolute stereostructures also been elucidated on the basis of their spectral data and some chemical evidence together with an X-ray crystallographic analysis of the p-bromobenzoate derived from euphornin. Furthermore, their conformations have also been discussed.",

author = "Yoshikazu Shizuri and Seiji Kosemura and Jiro Ohtsuka and Yukimasa Terada and Shosuke Yamamura and Shigeru Ohba and Masatoki Ito and Yoshihiko Saito",

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doi = "10.1016/S0040-4039(01)91548-5",

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T1 - Structural and conformational studies on euphornin and related diterpenes

AU - Shizuri, Yoshikazu

AU - Kosemura, Seiji

AU - Ohtsuka, Jiro

AU - Terada, Yukimasa

AU - Yamamura, Shosuke

AU - Ohba, Shigeru

AU - Ito, Masatoki

AU - Saito, Yoshihiko

PY - 1984

Y1 - 1984

N2 - In addition to euphornin, three new toxic substances (euphornins A, B and C) have been isolated from the plant Euphorbia helioscopia L., and their absolute stereostructures also been elucidated on the basis of their spectral data and some chemical evidence together with an X-ray crystallographic analysis of the p-bromobenzoate derived from euphornin. Furthermore, their conformations have also been discussed.

AB - In addition to euphornin, three new toxic substances (euphornins A, B and C) have been isolated from the plant Euphorbia helioscopia L., and their absolute stereostructures also been elucidated on the basis of their spectral data and some chemical evidence together with an X-ray crystallographic analysis of the p-bromobenzoate derived from euphornin. Furthermore, their conformations have also been discussed.

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U2 - 10.1016/S0040-4039(01)91548-5

DO - 10.1016/S0040-4039(01)91548-5

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VL - 25

SP - 1155

EP - 1158

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 11

ER -

Structural and conformational studies on euphornin and related diterpenes

Abstract

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