Structural elucidation of novel phosphocholine-containing glycosylinositol-phosphoceramides in filamentus fungi: (2). Spectral analysis of the sugar-inositol portion by 2D-NMR

Junko Yamada-Hada; Noriyasu Hada; Kazuhiro Aoki; Kenji Yamamoto; Tadahiro Takeda

doi:10.1248/cpb.52.473

Structural elucidation of novel phosphocholine-containing glycosylinositol-phosphoceramides in filamentus fungi: (2). Spectral analysis of the sugar-inositol portion by 2D-NMR

Junko Yamada-Hada, Noriyasu Hada, Kazuhiro Aoki, Kenji Yamamoto, Tadahiro Takeda

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

The sugar-inositol portion of the novel glycosylinositol-phosphoceramides, ZGL1 and ZGL2, from the filamentus fungi, Acremonium sp., were elucidated by a combination of NMR techniques including ¹H-¹H (COSY and HOHAHA) and ¹H-¹³C (HMQC and HMBC) spectroscopy. Further, examination of the ¹H-³¹P HMQC spectrum showed connectivity of inositol and ceramide through phosphate.

Original language	English
Pages (from-to)	473-476
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	52
Issue number	4
DOIs	https://doi.org/10.1248/cpb.52.473
Publication status	Published - 2004 Apr

Keywords

Acremonium sp.
Glycosylinositol-phosphoceramide
H- P HMQC
Spectral analysis

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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10.1248/cpb.52.473

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Structural elucidation of novel phosphocholine-containing glycosylinositol-phosphoceramides in filamentus fungi: (2). Spectral analysis of the sugar-inositol portion by 2D-NMR. / Yamada-Hada, Junko; Hada, Noriyasu; Aoki, Kazuhiro et al.
In: Chemical and Pharmaceutical Bulletin, Vol. 52, No. 4, 04.2004, p. 473-476.

Research output: Contribution to journal › Article › peer-review

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AU - Takeda, Tadahiro

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Structural elucidation of novel phosphocholine-containing glycosylinositol-phosphoceramides in filamentus fungi: (2). Spectral analysis of the sugar-inositol portion by 2D-NMR

Abstract

Keywords

ASJC Scopus subject areas

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