Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from an actinomycete

K. Suenaga; S. Kokubo; C. Shinohara; T. Tsuji; D. Uemura

doi:10.1016/S0040-4039(99)00050-7

Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from an actinomycete

K. Suenaga, S. Kokubo, C. Shinohara, T. Tsuji, D. Uemura

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

Two new lipopeptides, amamistatins A (1) and B, were isolated from an actinomycete. The absolute stereostructure of 1 was determined by spectroscopic and chemical analyses. Amamistatins A (1) and B showed growth inhibition for human tumor cell lines.

Original language	English
Pages (from-to)	1945-1948
Number of pages	4
Journal	Tetrahedron Letters
Volume	40
Issue number	10
DOIs	https://doi.org/10.1016/S0040-4039(99)00050-7
Publication status	Published - 1999 Mar 5
Externally published	Yes

Keywords

Degradation
Oxazoles
Peptides
Stereochemistry

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(99)00050-7

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title = "Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from an actinomycete",

abstract = "Two new lipopeptides, amamistatins A (1) and B, were isolated from an actinomycete. The absolute stereostructure of 1 was determined by spectroscopic and chemical analyses. Amamistatins A (1) and B showed growth inhibition for human tumor cell lines.",

keywords = "Degradation, Oxazoles, Peptides, Stereochemistry",

author = "K. Suenaga and S. Kokubo and C. Shinohara and T. Tsuji and D. Uemura",

note = "Funding Information: Acknowledgment. This work was supported in part by Wako Pure Chemical Industries Ltd. and by Grants-in-Aid for Scientific Research from the Ministry of Education, Science, Sports, and Culture, Japan.",

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doi = "10.1016/S0040-4039(99)00050-7",

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T1 - Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from an actinomycete

AU - Suenaga, K.

AU - Kokubo, S.

AU - Shinohara, C.

AU - Tsuji, T.

AU - Uemura, D.

N1 - Funding Information: Acknowledgment. This work was supported in part by Wako Pure Chemical Industries Ltd. and by Grants-in-Aid for Scientific Research from the Ministry of Education, Science, Sports, and Culture, Japan.

PY - 1999/3/5

Y1 - 1999/3/5

N2 - Two new lipopeptides, amamistatins A (1) and B, were isolated from an actinomycete. The absolute stereostructure of 1 was determined by spectroscopic and chemical analyses. Amamistatins A (1) and B showed growth inhibition for human tumor cell lines.

AB - Two new lipopeptides, amamistatins A (1) and B, were isolated from an actinomycete. The absolute stereostructure of 1 was determined by spectroscopic and chemical analyses. Amamistatins A (1) and B showed growth inhibition for human tumor cell lines.

KW - Degradation

KW - Oxazoles

KW - Peptides

KW - Stereochemistry

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U2 - 10.1016/S0040-4039(99)00050-7

DO - 10.1016/S0040-4039(99)00050-7

M3 - Article

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SN - 0040-4039

VL - 40

SP - 1945

EP - 1948

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 10

ER -

Structures of amamistatins A and B, novel growth inhibitors of human tumor cell lines from an actinomycete

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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