Studies on the constituents of Leonotis nepetaefolia

Y. Narukawa, N. Shimizu, T. Takeda

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


Three new acylated iridoids were isolatad from a methanol extract of Leonotis nepetaefolia R. Br. (Labiatae). Their structures were elucidated as 10-O-(cis-3, 4-dimethoxycinnamoyl) geniposidic acid (2), 10-O-(trans-feruroyl) geniposidic acid (3) and 10-O-(trans-caffeoyl) geniposidic acid (4) on the basis of the spectroscopic data. Antioxidative activities of the compounds were measured by the α, α-diphenyl-β-picrylhydrazyl (DPPH) method. The new iridoid glycoside, 10-O-(trans-caffeoyl) geniposidic acid showed a strong antioxidative activity.

Original languageEnglish
Pages (from-to)79-82
Number of pages4
JournalNatural Medicines
Issue number2
Publication statusPublished - 2001


  • Antioxidative activity
  • Iridoid glycoside
  • Labiatae
  • Leonotis nepetaefolia

ASJC Scopus subject areas

  • Molecular Medicine


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