Abstract
Ganciclovir-resistant cytomegalovirus infection is sometimes life-threatening for organ transplant recipients. Foscarnet is an alternative, although it may potentially worsen the preexistent impaired renal function. Here we report the case of a successful low-dose leflunomide treatment in a kidney transplant recipient with very high viral replication, who underwent kidney transplantation 10 years before. Administering 10 mg leflunomide daily for 5 months without a loading dose completely cleared the ganciclovir-resistant cytomegalovirus strains.
| Original language | English |
|---|---|
| Pages (from-to) | 133-138 |
| Number of pages | 6 |
| Journal | Journal of Clinical Virology |
| Volume | 82 |
| DOIs | |
| Publication status | Published - 2016 Sept 1 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Cytomegalovirus
- Ganciclovir-resistance
- Impaired renal function
- Kidney transplantation
- Leflunomide
ASJC Scopus subject areas
- Virology
- Infectious Diseases
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