Successful treatment of breakthrough disseminated Trichosporon asahii fungemia in a patient with acute myeloid leukemia receiving itraconazole prophylaxis

Daiki Karigane; Masatoshi Sakurai; Emiko Matsuyama; Kentaro Ide; Sakiko Yamamoto-Takeuchi; Toyoko Inazumi; Sumiko Kohashi

doi:10.1016/j.mmcr.2017.11.006

Successful treatment of breakthrough disseminated Trichosporon asahii fungemia in a patient with acute myeloid leukemia receiving itraconazole prophylaxis

Daiki Karigane, Masatoshi Sakurai, Emiko Matsuyama, Kentaro Ide, Sakiko Yamamoto-Takeuchi, Toyoko Inazumi, Sumiko Kohashi

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

We encountered a case of a 73-year-old man with acute myeloid leukemia who developed Trichosporon asahii systemic infection while on itraconazole prophylaxis during severe neutropenia. Cryptococcal antigen was useful for diagnosis. Although itraconazole was ineffective in protecting against trichosporonosis, treatment was successful with voriconazole following liposomal amphotericin B.

Original language	English
Pages (from-to)	1-3
Number of pages	3
Journal	Medical Mycology Case Reports
Volume	20
DOIs	https://doi.org/10.1016/j.mmcr.2017.11.006
Publication status	Published - 2018 Jun
Externally published	Yes

Keywords

Cryptococcal antigen
Itraconazole
Liposomal amphotericin B
Trichosporon asahii
Voriconazole

ASJC Scopus subject areas

Microbiology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.mmcr.2017.11.006

Cite this

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title = "Successful treatment of breakthrough disseminated Trichosporon asahii fungemia in a patient with acute myeloid leukemia receiving itraconazole prophylaxis",

abstract = "We encountered a case of a 73-year-old man with acute myeloid leukemia who developed Trichosporon asahii systemic infection while on itraconazole prophylaxis during severe neutropenia. Cryptococcal antigen was useful for diagnosis. Although itraconazole was ineffective in protecting against trichosporonosis, treatment was successful with voriconazole following liposomal amphotericin B.",

keywords = "Cryptococcal antigen, Itraconazole, Liposomal amphotericin B, Trichosporon asahii, Voriconazole",

author = "Daiki Karigane and Masatoshi Sakurai and Emiko Matsuyama and Kentaro Ide and Sakiko Yamamoto-Takeuchi and Toyoko Inazumi and Sumiko Kohashi",

note = "Publisher Copyright: {\textcopyright} 2017 The Authors",

year = "2018",

month = jun,

doi = "10.1016/j.mmcr.2017.11.006",

language = "English",

volume = "20",

pages = "1--3",

journal = "Medical Mycology Case Reports",

issn = "2211-7539",

publisher = "Elsevier BV",

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TY - JOUR

T1 - Successful treatment of breakthrough disseminated Trichosporon asahii fungemia in a patient with acute myeloid leukemia receiving itraconazole prophylaxis

AU - Karigane, Daiki

AU - Sakurai, Masatoshi

AU - Matsuyama, Emiko

AU - Ide, Kentaro

AU - Yamamoto-Takeuchi, Sakiko

AU - Inazumi, Toyoko

AU - Kohashi, Sumiko

PY - 2018/6

Y1 - 2018/6

N2 - We encountered a case of a 73-year-old man with acute myeloid leukemia who developed Trichosporon asahii systemic infection while on itraconazole prophylaxis during severe neutropenia. Cryptococcal antigen was useful for diagnosis. Although itraconazole was ineffective in protecting against trichosporonosis, treatment was successful with voriconazole following liposomal amphotericin B.

AB - We encountered a case of a 73-year-old man with acute myeloid leukemia who developed Trichosporon asahii systemic infection while on itraconazole prophylaxis during severe neutropenia. Cryptococcal antigen was useful for diagnosis. Although itraconazole was ineffective in protecting against trichosporonosis, treatment was successful with voriconazole following liposomal amphotericin B.

KW - Cryptococcal antigen

KW - Itraconazole

KW - Liposomal amphotericin B

KW - Trichosporon asahii

KW - Voriconazole

UR - http://www.scopus.com/inward/record.url?scp=85037625814&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85037625814&partnerID=8YFLogxK

U2 - 10.1016/j.mmcr.2017.11.006

DO - 10.1016/j.mmcr.2017.11.006

M3 - Article

AN - SCOPUS:85037625814

SN - 2211-7539

VL - 20

SP - 1

EP - 3

JO - Medical Mycology Case Reports

JF - Medical Mycology Case Reports

ER -

Successful treatment of breakthrough disseminated Trichosporon asahii fungemia in a patient with acute myeloid leukemia receiving itraconazole prophylaxis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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