Successful treatment of lupus protein-losing enteropathy with belimumab: A case report

Marenori Kojima; Hironari Hanaoka; Kaito Aoki; Hiromi Matsushita; Hiroshi Ito; Hidehiro Yamada

doi:10.1093/mrcr/rxae010

Successful treatment of lupus protein-losing enteropathy with belimumab: A case report

Marenori Kojima
, Hironari Hanaoka
, Kaito Aoki
, Hiromi Matsushita
, Hiroshi Ito
, Hidehiro Yamada

Department of Internal Medicine (Rheumatology)

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Lupus protein-losing enteropathy (LUPLE) is a rare condition in patients with systemic lupus erythematosus (SLE). Since the causes and exact pathological mechanism have not been elucidated, appropriate treatment has not been determined. Here, we report the case of a 69-year-old woman with systemic lupus erythematosus who developed LUPLE which was successfully treated with belimumab without an increase in glucocorticoid dose.This case suggests that belimumab monotherapy may be a treatment option for LUPLE.

Original language	English
Pages (from-to)	264-266
Number of pages	3
Journal	Modern Rheumatology Case Reports
Volume	8
Issue number	2
DOIs	https://doi.org/10.1093/mrcr/rxae010
Publication status	Published - 2024 Jul 1

Keywords

Systemic lupus erythematosus
belimumab
protein-losing enteropathy

ASJC Scopus subject areas

Rheumatology

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10.1093/mrcr/rxae010

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title = "Successful treatment of lupus protein-losing enteropathy with belimumab: A case report",

abstract = "Lupus protein-losing enteropathy (LUPLE) is a rare condition in patients with systemic lupus erythematosus (SLE). Since the causes and exact pathological mechanism have not been elucidated, appropriate treatment has not been determined. Here, we report the case of a 69-year-old woman with systemic lupus erythematosus who developed LUPLE which was successfully treated with belimumab without an increase in glucocorticoid dose.This case suggests that belimumab monotherapy may be a treatment option for LUPLE.",

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AU - Kojima, Marenori

AU - Hanaoka, Hironari

AU - Aoki, Kaito

AU - Matsushita, Hiromi

AU - Ito, Hiroshi

AU - Yamada, Hidehiro

N1 - Publisher Copyright: © Japan College of Rheumatology 2024.

PY - 2024/7/1

Y1 - 2024/7/1

N2 - Lupus protein-losing enteropathy (LUPLE) is a rare condition in patients with systemic lupus erythematosus (SLE). Since the causes and exact pathological mechanism have not been elucidated, appropriate treatment has not been determined. Here, we report the case of a 69-year-old woman with systemic lupus erythematosus who developed LUPLE which was successfully treated with belimumab without an increase in glucocorticoid dose.This case suggests that belimumab monotherapy may be a treatment option for LUPLE.

AB - Lupus protein-losing enteropathy (LUPLE) is a rare condition in patients with systemic lupus erythematosus (SLE). Since the causes and exact pathological mechanism have not been elucidated, appropriate treatment has not been determined. Here, we report the case of a 69-year-old woman with systemic lupus erythematosus who developed LUPLE which was successfully treated with belimumab without an increase in glucocorticoid dose.This case suggests that belimumab monotherapy may be a treatment option for LUPLE.

KW - Systemic lupus erythematosus

KW - belimumab

KW - protein-losing enteropathy

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ER -

Successful treatment of lupus protein-losing enteropathy with belimumab: A case report

Abstract

Keywords

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