TY - JOUR
T1 - Successful treatment of subfoveal choroidal neovascularization associated with combined hamartoma of the retina and retinal pigment epithelium
AU - Inoue, Makoto
AU - Noda, Koushuke
AU - Ishida, Susumu
AU - Yamaguchi, Takefumi
AU - Nagai, Norihiro
AU - Shinoda, Kei
AU - Shinoda, Hajime
AU - Oguchi, Yoshihisa
PY - 2004/7
Y1 - 2004/7
N2 - Purpose To describe a patient with subfoveal choroidal neovascularization (CNV) associated with combined hamartoma of the retina and retinal pigment epithelium (CHRRPE), treated successfully by submacular surgery. Design Interventional case report. Methods A 12-year-old girl was referred to our clinic for evaluation. Visual acuity was 20/30 in the affected left eye. Ophthalmoscopy disclosed juxtapapillary CHRRPE and subfoveal pigmented CNV. Vitreous surgery was carried out because of visual deterioration to 20/60. Results The posterior vitreous was strongly attached to glial tissue at the superior margin of the optic disk in the CHRRPE region. The CNV, which was not connected with the CHRRPE, was carefully removed, resulting in visual improvement to 20/20 5 months after surgery. Histologically, the excised membrane showed fibroblast-rich cellular component and a type 2 configuration. Conclusion Submacular surgery can be effective for the treatment of secondary CNV associated with CHRRPE.
AB - Purpose To describe a patient with subfoveal choroidal neovascularization (CNV) associated with combined hamartoma of the retina and retinal pigment epithelium (CHRRPE), treated successfully by submacular surgery. Design Interventional case report. Methods A 12-year-old girl was referred to our clinic for evaluation. Visual acuity was 20/30 in the affected left eye. Ophthalmoscopy disclosed juxtapapillary CHRRPE and subfoveal pigmented CNV. Vitreous surgery was carried out because of visual deterioration to 20/60. Results The posterior vitreous was strongly attached to glial tissue at the superior margin of the optic disk in the CHRRPE region. The CNV, which was not connected with the CHRRPE, was carefully removed, resulting in visual improvement to 20/20 5 months after surgery. Histologically, the excised membrane showed fibroblast-rich cellular component and a type 2 configuration. Conclusion Submacular surgery can be effective for the treatment of secondary CNV associated with CHRRPE.
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U2 - 10.1016/j.ajo.2004.02.020
DO - 10.1016/j.ajo.2004.02.020
M3 - Article
C2 - 15234304
AN - SCOPUS:3042698666
SN - 0002-9394
VL - 138
SP - 155
EP - 156
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 1
ER -