TY - JOUR
T1 - Surgical punctal occlusion with a high heat-energy releasing cautery device for severe dry eye with recurrent punctal plug extrusion
AU - Ohba, Emii
AU - Dogru, Murat
AU - Hosaka, Eri
AU - Yamazaki, Asako
AU - Asaga, Rie
AU - Tatematsu, Yukako
AU - Ogawa, Yoko
AU - Tsubota, Kazuo
AU - Goto, Eiki
N1 - Funding Information:
Publication of this article was Supported by Grant 18070501 from the Japanese Ministry of Health, Labour and Welfare , Tokyo, Japan. The authors indicate no financial conflict of interest. Involved in Design of study (E.O., M.D., E.G.); Conduct of study (Y.O., K.T., E.G.); Collection and analysis of data (E.H., A.Y., R.A., Y.T., Y.O., E.G.); and Approval of manuscript (Y.O., K.T., E.G.). This research followed the tenets of the Declaration of Helsinki, and informed consent was obtained from all the subjects after explanation of the nature and possible consequences of the study. Institutional review board approval was obtained at Tsurumi University. This clinical trial was registered to Japan Pharmaceutical Information Center (Tokyo, Japan, Japic CTI-060313).
PY - 2011/3
Y1 - 2011/3
N2 - • Purpose: To report the rate of recanalization and the efficacy of punctal occlusion surgery with a high heat-energy-releasing cautery device in patients with severe dry eye disease and recurrent punctal plug extrusion. • Design: Prospective, interventional case series. • Methods: Seventy puncta from 44 eyes of 28 dry eye patients underwent punctal occlusion with thermal cautery. All patients had a history of recurrent punctal plug extrusion. A high heat-energy-releasing thermal cautery device (Optemp II V; Alcon Japan) was used for punctal occlusion surgery. Symptom scores, best-corrected visual acuity, fluorescein staining score, rose bengal staining score, tear film break-up time, and Schirmer test values were compared before and 3 months after the surgery. Rate of punctal recanalization also was examined. • Results: Three months after surgical cauterization, symptom score decreased from 3.9 ± 0.23 to 0.56 ± 0.84 (P < .0001). Logarithm of the minimal angle of resolution best-corrected visual acuity improved from 0.11 ± 0.30 to 0.013 ± 0.22 (P = .003). Fluorescein staining score, rose bengal staining score, tear film break-up time, and the Schirmer test value also improved significantly after the surgery. Only 1 of 70 puncta recanalized after thermal cauterization (1.4%). • Conclusions: Punctal occlusion with the high heat-energy-releasing cautery device not only was associated with a low recanalization rate, but also with improvements in ocular surface wetness and better visual acuity.
AB - • Purpose: To report the rate of recanalization and the efficacy of punctal occlusion surgery with a high heat-energy-releasing cautery device in patients with severe dry eye disease and recurrent punctal plug extrusion. • Design: Prospective, interventional case series. • Methods: Seventy puncta from 44 eyes of 28 dry eye patients underwent punctal occlusion with thermal cautery. All patients had a history of recurrent punctal plug extrusion. A high heat-energy-releasing thermal cautery device (Optemp II V; Alcon Japan) was used for punctal occlusion surgery. Symptom scores, best-corrected visual acuity, fluorescein staining score, rose bengal staining score, tear film break-up time, and Schirmer test values were compared before and 3 months after the surgery. Rate of punctal recanalization also was examined. • Results: Three months after surgical cauterization, symptom score decreased from 3.9 ± 0.23 to 0.56 ± 0.84 (P < .0001). Logarithm of the minimal angle of resolution best-corrected visual acuity improved from 0.11 ± 0.30 to 0.013 ± 0.22 (P = .003). Fluorescein staining score, rose bengal staining score, tear film break-up time, and the Schirmer test value also improved significantly after the surgery. Only 1 of 70 puncta recanalized after thermal cauterization (1.4%). • Conclusions: Punctal occlusion with the high heat-energy-releasing cautery device not only was associated with a low recanalization rate, but also with improvements in ocular surface wetness and better visual acuity.
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U2 - 10.1016/j.ajo.2010.08.045
DO - 10.1016/j.ajo.2010.08.045
M3 - Article
C2 - 21232733
AN - SCOPUS:79951811073
SN - 0002-9394
VL - 151
SP - 483-487.e1
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 3
ER -