Surgically treated Cronkhite-Canada syndrome associated with gastric cancer

Tomohisa Egawa, Tetsuro Kubota, Yoshihide Otani, Naoto Kurihara, Sadanori Abe, Masaru Kimata, Joh Tokuyama, Norihito Wada, Kazuhiro Suganuma, Yuusuke Kuwano, Koichiro Kumai, Yoshinori Sugino, Makio Mukai, Masaki Kitajima

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34 Citations (Scopus)


Cronkhite-Canada syndrome is generally accepted to be a benign disorder, with 374 reported cases to the present. Worldwide, there have been 18 previously reported cases of Cronkhite-Canada syndrome associated with gastric cancer. In this report we describe a case of a 52-year-old man with the clinical features of Cronkhite-Canada syndrome combined with gastric cancer. Although the gastric tumor was located at the antrum of the stomach, we performed a total gastrectomy because of the edematous swelling and high risk of malignancy in the remnant stomach. As Cronkhite-Canada syndrome may be a premalignant condition for gastric cancer, as well as for colorectal cancer, we suggest periodic examination of the stomach, colon, and rectum for patients with Cronkhite-Canada syndrome.

Original languageEnglish
Pages (from-to)156-160
Number of pages5
JournalGastric Cancer
Issue number3
Publication statusPublished - 2000
Externally publishedYes


  • Cronkhite-Canada syndrome
  • Gastric cancer

ASJC Scopus subject areas

  • Oncology
  • Gastroenterology
  • Cancer Research


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