TY - GEN
T1 - Synchronization control for circadian rhythm of drosophila with flatness-based adaptive control
AU - Kusumi, Tetsuya
AU - Ohmori, Hiromitsu
PY - 2007/12/1
Y1 - 2007/12/1
N2 - Recently, developing molecular biology and system biology, the mechanism of the circadian rhythm in which the inside of the body rhythm of the living thing is ruled is being clarified at the cell level. On the other hand, it is said that various sicknesses are related in the medicine and pharmacology to the disorder of the circadian rhythm. Therefore, it is thought that to restore an altered rhythm is a goal of these therapies. In this paper, we study the 10-states circadian model of Drosophila and propose a close-loop control based on flatness-based adaptive control to achieve circadian rhythm restoration.
AB - Recently, developing molecular biology and system biology, the mechanism of the circadian rhythm in which the inside of the body rhythm of the living thing is ruled is being clarified at the cell level. On the other hand, it is said that various sicknesses are related in the medicine and pharmacology to the disorder of the circadian rhythm. Therefore, it is thought that to restore an altered rhythm is a goal of these therapies. In this paper, we study the 10-states circadian model of Drosophila and propose a close-loop control based on flatness-based adaptive control to achieve circadian rhythm restoration.
KW - Adaptive control
KW - Circadian rhythm
KW - Flatness-based control
KW - Synchronization control
KW - System biology
UR - http://www.scopus.com/inward/record.url?scp=50249120750&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=50249120750&partnerID=8YFLogxK
U2 - 10.1109/SICE.2007.4421177
DO - 10.1109/SICE.2007.4421177
M3 - Conference contribution
AN - SCOPUS:50249120750
SN - 4907764286
SN - 9784907764289
T3 - Proceedings of the SICE Annual Conference
SP - 1258
EP - 1262
BT - SICE Annual Conference, SICE 2007
T2 - SICE(Society of Instrument and Control Engineers)Annual Conference, SICE 2007
Y2 - 17 September 2007 through 20 September 2007
ER -