Synchronized control for circadian rhythm based on the central clock model of drosophila

Yuta Katakura, Hiromitsu Ohmori

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Orcadian rhythm governed by an oscillating set of genes called the central clock has become an important concern in biology, and it is said that to restore an altered rhythm is a goal of cancer therapy beyond the destruction of tumor cells. In this paper, we study the central clock model of Drosophila, which is a nonlinear oscillator model. We propose a close-loop control based on flatness-based adaptive control, an open-loop control, to achieve circadian rhythm restoration.

Original languageEnglish
Title of host publication2006 SICE-ICASE International Joint Conference
Number of pages4
Publication statusPublished - 2006 Dec 1
Event2006 SICE-ICASE International Joint Conference - Busan, Korea, Republic of
Duration: 2006 Oct 182006 Oct 21

Publication series

Name2006 SICE-ICASE International Joint Conference


Other2006 SICE-ICASE International Joint Conference
Country/TerritoryKorea, Republic of


  • Nonlinear system
  • Orcadian rhythm

ASJC Scopus subject areas

  • Computer Science Applications
  • Control and Systems Engineering
  • Electrical and Electronic Engineering


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