TY - GEN
T1 - Synchronized control for circadian rhythm based on the central clock model of drosophila
AU - Katakura, Yuta
AU - Ohmori, Hiromitsu
PY - 2006
Y1 - 2006
N2 - Orcadian rhythm governed by an oscillating set of genes called the central clock has become an important concern in biology, and it is said that to restore an altered rhythm is a goal of cancer therapy beyond the destruction of tumor cells. In this paper, we study the central clock model of Drosophila, which is a nonlinear oscillator model. We propose a close-loop control based on flatness-based adaptive control, an open-loop control, to achieve circadian rhythm restoration.
AB - Orcadian rhythm governed by an oscillating set of genes called the central clock has become an important concern in biology, and it is said that to restore an altered rhythm is a goal of cancer therapy beyond the destruction of tumor cells. In this paper, we study the central clock model of Drosophila, which is a nonlinear oscillator model. We propose a close-loop control based on flatness-based adaptive control, an open-loop control, to achieve circadian rhythm restoration.
KW - Nonlinear system
KW - Orcadian rhythm
UR - http://www.scopus.com/inward/record.url?scp=34250771741&partnerID=8YFLogxK
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U2 - 10.1109/SICE.2006.314985
DO - 10.1109/SICE.2006.314985
M3 - Conference contribution
AN - SCOPUS:34250771741
SN - 8995003855
SN - 9788995003855
T3 - 2006 SICE-ICASE International Joint Conference
SP - 2358
EP - 2361
BT - 2006 SICE-ICASE International Joint Conference
T2 - 2006 SICE-ICASE International Joint Conference
Y2 - 18 October 2006 through 21 October 2006
ER -